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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by fenix on February 24, 2006, at 8:49:36
It has to do with drug metabolism:
http://www.mhc.com/Cytochromes/GFJ.HTML
This is basically a summary of the information contained in the above link:
Posted by fenix on February 24, 2006, at 11:40:45
In reply to Drug Interactions With Grapefruit, posted by fenix on February 24, 2006, at 8:49:36
And more...
CYP3A inhibition recovery time from single doses of grapefruit juice (midazolam is used as the substrate):
Also, here is a link of more reference material on grapefruit and various drug interactions:
http://powernetdesign.com/grapefruit/references/index.htm#ref41
Posted by Phillipa on February 24, 2006, at 19:28:06
In reply to Re: Drug Interactions With Grapefruit, posted by fenix on February 24, 2006, at 11:40:45
I always wondered why they said no grapefruit juice with meds. Fondly, Phillipa
Posted by fenix on February 25, 2006, at 16:19:49
In reply to Re: Drug Interactions With Grapefruit » fenix, posted by Phillipa on February 24, 2006, at 19:28:06
> I always wondered why they said no grapefruit juice with meds. Fondly, Phillipa
Yeah, me too and I eventually decided to look up stuff on it. I also did a search on dr-bob.org for "grapefruit" and then I found out that there were already some topics on it from the past.
It fascinates me really; the whole thing with the grapefruit and all. It is just a humble fruit yet it can do some interesting things when you eat it concomitantly with certain medications.
Posted by Larry Hoover on February 26, 2006, at 12:42:38
In reply to Re: Drug Interactions With Grapefruit, posted by fenix on February 25, 2006, at 16:19:49
> > I always wondered why they said no grapefruit juice with meds. Fondly, Phillipa
>
> Yeah, me too and I eventually decided to look up stuff on it. I also did a search on dr-bob.org for "grapefruit" and then I found out that there were already some topics on it from the past.
>
> It fascinates me really; the whole thing with the grapefruit and all. It is just a humble fruit yet it can do some interesting things when you eat it concomitantly with certain medications.The grapefruit effect is an inhibition of a specific liver enzyme. That same enzyme can also be induced (speeded up) by other meds. One example of that would be St. John's wort. Grapefruit and SJW are on opposite ends of the teeter-totter.
Lar
Posted by fenix on February 28, 2006, at 5:01:44
In reply to Re: Drug Interactions With Grapefruit » fenix, posted by Larry Hoover on February 26, 2006, at 12:42:38
I know.
Posted by Greif on February 28, 2006, at 23:34:05
In reply to Re: Drug Interactions With Grapefruit » fenix, posted by Larry Hoover on February 26, 2006, at 12:42:38
Tobaacco effects on liver also affect dissapation of benzos...so for you smokers try quitting...you will get better and longer effects not to mention health benefits.
This is the end of the thread.
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