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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by ed_uk on January 27, 2006, at 14:33:47
Clorazepate (Tranxene) will be discontinued in the UK in February.
Ed
Posted by krybrahaha78 on January 28, 2006, at 1:17:46
In reply to Tranxene, posted by ed_uk on January 27, 2006, at 14:33:47
that sux, that is a good drug. Is there any reason why they are discontinuing it?
Posted by ed_uk on January 28, 2006, at 7:18:07
In reply to Re: Tranxene, posted by krybrahaha78 on January 28, 2006, at 1:17:46
Hi
>Is there any reason why they are discontinuing it?
....because so few people take it. It isn't available on the National Health Service so it's very rarely prescribed here. Diazepam (Valium) is the prefered benzo.
AFAIK, Tranxene is still available in the US. It's being discontinued in the UK. Don't know about anywhere else.
Regards
Ed
Posted by ed_uk on January 28, 2006, at 8:11:57
In reply to Re: Tranxene, posted by krybrahaha78 on January 28, 2006, at 1:17:46
If you liked Tranxene you'd probably like Valium or Librium. Ever tried them? I believe you're on Klonopin at the moment.
Ed
Posted by john berk on January 28, 2006, at 16:39:39
In reply to Re: Tranxene » krybrahaha78, posted by ed_uk on January 28, 2006, at 8:11:57
i took tranxene 20 years ago,probably my first anxiety med as a teen , i have yet to hear any of my friends ever mention it, your right Ed, def not a popular med, even here in the states, but it was as good or better than valium for me, i'm also now on klonopin..john
Posted by krybrahaha78 on January 28, 2006, at 17:53:06
In reply to Re: Tranxene » krybrahaha78, posted by ed_uk on January 28, 2006, at 8:11:57
ive taken valium, but it never even touched my anxiety, never tried librium though.
> If you liked Tranxene you'd probably like Valium or Librium. Ever tried them? I believe you're on Klonopin at the moment.
>
> Ed
Posted by krybrahaha78 on January 28, 2006, at 17:54:56
In reply to Re: Tranxene » krybrahaha78, posted by ed_uk on January 28, 2006, at 8:11:57
I got tolerant to the effects of tranxene rather quickly so i had to get off it. My doc put me on klonopin and so far, i havent grown any tolerance to it whatsoever, is that common?
> If you liked Tranxene you'd probably like Valium or Librium. Ever tried them? I believe you're on Klonopin at the moment.
>
> Ed
Posted by ed_uk on January 29, 2006, at 12:39:53
In reply to Re: Tranxene, posted by krybrahaha78 on January 28, 2006, at 17:53:06
Hi K
>ive taken valium, but it never even touched my anxiety
Probably because the dose was too low. Diazepam (Valium) is metabolised to desmethyldiazepam in the liver. Clorazepate (Tranxene) is a pro-drug of desmethyldiazepam ie. it works because it's converted to desmethyldiazepam in the body.
Ed
Posted by ed_uk on January 29, 2006, at 12:42:22
In reply to Re: Tranxene quicker tolerance than klonopin?, posted by krybrahaha78 on January 28, 2006, at 17:54:56
Hi
>Tranxene quicker tolerance than klonopin?
It's difficult to say. I'm tempted to believe that clonazepam seems to work better mainly because it's more potent, and tends to be prescribed at comparatively high doses.
Regards
Ed
Posted by ed_uk on January 29, 2006, at 12:44:22
In reply to Re: Tranxene, posted by krybrahaha78 on January 28, 2006, at 17:53:06
Some people find that they need to take up to 20mg diazepam (Valium) to replace 1mg clonazepam (Klonopin). Diazepam would seem ineffective unless the dose was adequate.
Ed
Posted by yxibow on January 31, 2006, at 1:32:20
In reply to Re: Tranxene » krybrahaha78, posted by ed_uk on January 29, 2006, at 12:44:22
> Some people find that they need to take up to 20mg diazepam (Valium) to replace 1mg clonazepam (Klonopin). Diazepam would seem ineffective unless the dose was adequate.
>
> EdThat's pretty much my experience and actually the standard dose translation from what I know.. 10 Valium = 0.5 Klonopin.
I took Tranxene at one point. It's a thrice daily drug with a noticeable short half life.
This is the end of the thread.
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