Psycho-Babble Medication Thread 591879

Shown: posts 1 to 5 of 5. This is the beginning of the thread.

 

Combining Lofepramine with an MAOI?

Posted by Tom Twilight on December 24, 2005, at 12:33:03

Its Christmas Eve and my mood has suddenly slipped drasticly, great! :(

I'm currently on Marplan, which I don't really want to discontinue before taking another AD

The options of what you can combine with an MAOI are a bit limmited, especially in the UK

Presumably Lofepramine can be safely combined with MAOI as its similar to Desipramine
Which is the only TCA its completely safe to combine with an MAOI

Is that right?

 

Re: Combining Lofepramine with an MAOI?

Posted by Declan on December 24, 2005, at 12:53:45

In reply to Combining Lofepramine with an MAOI?, posted by Tom Twilight on December 24, 2005, at 12:33:03

The Christmas eve mood slip followed by the Christmas day wipe out. Can't you enjoy that lovely cold weather you should be having? 30 degrees here and 80% humidity. So the Marplan must help a bit, or you wouldn't wanna continue it. You must feel crook if you're thinking of TCAs plus MAOIs. The sun's just up, it looks vaguely like the end of the world, very striking.
See ya
Declan

 

Christmas depression-Please help!-Ed?

Posted by Tom Twilight on December 24, 2005, at 14:17:14

In reply to Re: Combining Lofepramine with an MAOI?, posted by Declan on December 24, 2005, at 12:53:45

> So the Marplan must help a bit, or you wouldn't wanna continue it. You must feel crook if you're thinking of TCAs plus MAOIs.

Hey Declan

I think I owe you an email, better check

I'm not discontinueing the Marplan firstly because it is working well for anxiety, if not for social anxiety
Thats typical for me

I'm also scared of withdrawing from Marplan, don't know what it will be like.......
Also I need a backup plan, if I do withdraw
I don't want to be left completely high and dry

Don't what to do people

Wonder were Ed is?

 

Re: Christmas depression-Please help!-Ed? » Tom Twilight

Posted by Phillipa on December 24, 2005, at 15:55:10

In reply to Christmas depression-Please help!-Ed?, posted by Tom Twilight on December 24, 2005, at 14:17:14

I think I might know where Ed is. He said he was filling in for others at the pharmacy at Christmas so he may be working what time are they open to over in England? Fondly, Phillipa

 

Re: Combining Lofepramine with an MAOI? » Tom Twilight

Posted by Jedi on December 26, 2005, at 3:06:40

In reply to Combining Lofepramine with an MAOI?, posted by Tom Twilight on December 24, 2005, at 12:33:03

> Its Christmas Eve and my mood has suddenly slipped drasticly, great! :(
>
> I'm currently on Marplan, which I don't really want to discontinue before taking another AD
>
> The options of what you can combine with an MAOI are a bit limmited, especially in the UK
>
> Presumably Lofepramine can be safely combined with MAOI as its similar to Desipramine
> Which is the only TCA its completely safe to combine with an MAOI
>
> Is that right?

Hi Tom,
I've read that lofepramine is extensively metabolized to desipramine in the liver. I haven't studied it enough to know if it can be safely combined with a MAOI. There are effects of the medication other than from the metabolite desipramine. I have combined nortriptyline at 100mg with Nardil at 75mg. Nortriptyline is the major metabolite of amitriptyline. IMHO any of these combinations can be potentially dangerous and should only be administered by an expert in psychopharmacology.
Good Luck,
Jedi


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