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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by ghostshadow on December 13, 2005, at 10:45:27
i stsrted on 225 mg. effexor xr about 2 weeks ago after slightly more than 10 years of paxil. the paxil had long ago quit working, but nobody else cared so why should i? a friend made me promise to talk to my doc about my meds, and he switched me to effecor xr. so far no difference than before the change. Anyone else had a direct switch from an ssri, and what was the outcome? (only other psych drug i take is trazadone for ocd and to help me sleep.)
Posted by sm100378 on December 13, 2005, at 11:04:24
In reply to Effexor XR effectiveness, posted by ghostshadow on December 13, 2005, at 10:45:27
Hi,
I was never on paxil, but actually have a question for you. I recently have been put on Effexor XR 37.5 and have seen a change since day 1.
Is Effexor an SNRI and what is the difference between that and an SSRI?
Thanks> i stsrted on 225 mg. effexor xr about 2 weeks ago after slightly more than 10 years of paxil. the paxil had long ago quit working, but nobody else cared so why should i? a friend made me promise to talk to my doc about my meds, and he switched me to effecor xr. so far no difference than before the change. Anyone else had a direct switch from an ssri, and what was the outcome? (only other psych drug i take is trazadone for ocd and to help me sleep.)
Posted by ghostshadow on December 13, 2005, at 11:12:14
In reply to Re: Effexor XR effectiveness, posted by sm100378 on December 13, 2005, at 11:04:24
>An SSRI only works on seratonin in the brain, while an SNRI works on both seratonin and norepinephrine. My doc (whom i think is a quack but may be somewhat right this time) thinks i may have developed a tolerance to the ssri alone...
Hi,
>
> I was never on paxil, but actually have a question for you. I recently have been put on Effexor XR 37.5 and have seen a change since day 1.
>
> Is Effexor an SNRI and what is the difference between that and an SSRI?
>
>
> Thanks
>
>
>
> > i stsrted on 225 mg. effexor xr about 2 weeks ago after slightly more than 10 years of paxil. the paxil had long ago quit working, but nobody else cared so why should i? a friend made me promise to talk to my doc about my meds, and he switched me to effecor xr. so far no difference than before the change. Anyone else had a direct switch from an ssri, and what was the outcome? (only other psych drug i take is trazadone for ocd and to help me sleep.)
>
>
Posted by Bill LL on December 13, 2005, at 15:19:14
In reply to Re: Effexor XR effectiveness » sm100378, posted by ghostshadow on December 13, 2005, at 11:12:14
For some reason that comment "My doc (whom i think is a quack but may be somewhat right this time)" really made me laugh. I can identify with it since my last internist was so lame. But I switched and am extremely happy with the new one.
It's correct that Effexor affects serotonin at lower doses, then also affects non-ep at higher doses.
But docs don't know which of the 2 effects is more important. Even with SSRI's, docs know that they affect serotonin, but they don't know how this works to alleviate anxiety and/or depression.
But the bottom line is that both types of drugs are very effective with very minimal dangerous side effects.
Effexor is generally demonstrated to be a bit more effective than SSRI's in clinical trials. It's a very popular drug with docs since it usually works so well for both anxiety and depression. But you have to give it a couple of weeks to work to give it a fair trial.
> >An SSRI only works on seratonin in the brain, while an SNRI works on both seratonin and norepinephrine. My doc (whom i think is a quack but may be somewhat right this time) thinks i may have developed a tolerance to the ssri alone...
>
> Hi,
> >
> > I was never on paxil, but actually have a question for you. I recently have been put on Effexor XR 37.5 and have seen a change since day 1.
> >
> > Is Effexor an SNRI and what is the difference between that and an SSRI?
> >
> >
> > Thanks
> >
> >
> >
> > > i stsrted on 225 mg. effexor xr about 2 weeks ago after slightly more than 10 years of paxil. the paxil had long ago quit working, but nobody else cared so why should i? a friend made me promise to talk to my doc about my meds, and he switched me to effecor xr. so far no difference than before the change. Anyone else had a direct switch from an ssri, and what was the outcome? (only other psych drug i take is trazadone for ocd and to help me sleep.)
> >
> >
>
>
Posted by sm100378 on December 13, 2005, at 18:12:55
In reply to Re: Effexor XR effectiveness, posted by Bill LL on December 13, 2005, at 15:19:14
Referring to:
http://www.dr-bob.org/babble/20051203/msgs/587373.html
http://www.dr-bob.org/babble/20051203/msgs/587432.html
I am on Wellbutrin 300XL and Effexor 37.5XR, as well as Klonopin. Has anyone had to reduce/get off of Wellbutrin, since Wellbutrin has properties of a stimulant, which may keep anxiety around? And what was the replacement of Wellbutrin?(Keeping in mind Wellbutrin is one of the few anti-depressants that has a low % of sexual side effects).
Thanks much
Posted by Phillipa on December 13, 2005, at 22:46:54
In reply to Re: Effexor XR effectiveness (Linkadge, Anyone?), posted by sm100378 on December 13, 2005, at 18:12:55
I had to get off the wellbutrin it made me hypomanic and put me in the hospital last year. Fondly,Phillipa
Posted by ghostshadow on December 14, 2005, at 9:37:39
In reply to Re: Effexor XR effectiveness, posted by Bill LL on December 13, 2005, at 15:19:14
It has been at least a couple of weeks, and i still feel the same. I guess part of why i feel so frustrated is because so many people here are saying how much better they feel/felt at such a lower dosage. But i still feel like pulling a hole closed over me (and nobody would care or even notice) and absolutely everything sets me off. I never used to be short-tempered, and i hate it.
This is the end of the thread.
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