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Dr. Bob is Robert Hsiung, MD,
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Posted by gibber on December 11, 2005, at 21:56:44
I'm up to 45mg of Nardil with thankfully no side-effects yet. I'm finding it easier to take one 15mg pill in the morning and 2 pills at night. Would it be better to take them dispursed thoughout the day? Also it seems a few of the MAOIs have very short half-lives (2-3hrs) which is even less than Effexor. Is it because nardil is an irreversible MAOI that we don't experience withdrawal after a few hours or is the mechanism completely different?
I've had no real anti-depressive effects yet but its still real early.
Posted by gardenergirl on December 11, 2005, at 23:28:37
In reply to Into second week of Nardil, dosage question, posted by gibber on December 11, 2005, at 21:56:44
I have no idea of the technical answer to your question, but I can tell you what I did and do. When I take 45 mg, I take them about 8 hours apart, or one tablet three times a day. I'm currently on 60 mg, and I take one in the a.m., two in the early afternoon, and one at bedtime. It works for me, but I don't know what the recommended way to take them is.
gg
Posted by Jedi on December 12, 2005, at 4:06:15
In reply to Into second week of Nardil, dosage question, posted by gibber on December 11, 2005, at 21:56:44
> I'm up to 45mg of Nardil with thankfully no side-effects yet. I'm finding it easier to take one 15mg pill in the morning and 2 pills at night. Would it be better to take them dispursed thoughout the day? Also it seems a few of the MAOIs have very short half-lives (2-3hrs) which is even less than Effexor. Is it because nardil is an irreversible MAOI that we don't experience withdrawal after a few hours or is the mechanism completely different?
>
> I've had no real anti-depressive effects yet but its still real early.Hi,
The prescribing information from Pfizer says to take one 15mg tablet three times per day. I take between 75 and 90mg of Nardil currently and split it into two doses. I have experimented with taking the medication at different times, to try to avoid the late afternoon somnolence. I've even taken the entire dose at bedtime after titrating up to an effective dosage. It did not seem to make any difference, so I just do what is convienent for me.
I'm not sure on the medications half-life. It does alter MAO inhibition for a couple of weeks after stopping the med.Nardil® (phenelzine sulfate tablets, USP)
Nardil Full U.S. Prescribing Information (PDF)
http://www.pfizer.com/pfizer/download/uspi_nardil.pdfTake care,
Jedi
This is the end of the thread.
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