![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by linkadge on October 29, 2005, at 20:11:04
THe 5-ht1b autoreceptor may be too active in depression. Shock, some AD's and exercise decrease it. rTMS too.
http://biopsychiatry.com/serotonin/gene.html
Linkadge
Posted by SLS on October 29, 2005, at 20:48:19
In reply to 5-ht1b too active in depression, posted by linkadge on October 29, 2005, at 20:11:04
> THe 5-ht1b autoreceptor may be too active in depression. Shock, some AD's and exercise decrease it. rTMS too.
Where can I find stuff regarding the influence exercise has on 5-HT1b function. Is this a transient effect occuring acutely upon exercise or something that is gained only through chronic application.
Thanks.
- Scott
Posted by linkadge on October 29, 2005, at 21:34:36
In reply to Re: 5-ht1b too active in depression, posted by SLS on October 29, 2005, at 20:48:19
I'm looking for the study. I posted it a while ago, it was a study about some of the general effects of exercise on learned helplessness.
It basically said that a few weeks of wheel running lead to a significant downregulation of 5-ht1b autoreceptor expression, lasting as long as the mice exercised.
Linkadge
Posted by SLS on October 29, 2005, at 21:44:37
In reply to Re: 5-ht1b too active in depression, posted by linkadge on October 29, 2005, at 21:34:36
Thanks, Linkadge.
> I'm looking for the study. I posted it a while ago, it was a study about some of the general effects of exercise on learned helplessness.
You answered my question for me. Don't trouble yourself looking for the citation. That's a pretty strong argument for exercising.
> It basically said that a few weeks of wheel running lead to a significant downregulation of 5-ht1b autoreceptor expression, lasting as long as the mice exercised.
How are you doing, by the way?
- Scott
Posted by Phillipa on October 29, 2005, at 22:27:57
In reply to Re: 5-ht1b too active in depression, posted by SLS on October 29, 2005, at 21:44:37
Scott let's all chip in and get Link some mice. They multiple rapidly and I think he needs a pet. Fondly, Phillipa
Posted by linkadge on October 29, 2005, at 22:40:32
In reply to Re: 5-ht1b too active in depression, posted by SLS on October 29, 2005, at 21:44:37
I'm doing so-so. Good days and bad. I'm taking a little bit of lithium, hardly sufficiant.
Yourself ?
I think this was the study.
Greenwood, B.N., Foley, T.E., Day, H.E.W., Burhans, D., Brooks, L., Campeau, S., & Fleshner, M. (2005). Wheel running alters serotonin (5-HT) transporter, 5-HT1a, 5-HT1b, and alpha1b-adrenergic receptor mRNA in the rat
Linkadge
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.