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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by linkadge on September 16, 2005, at 20:25:57
http://biopsychiatry.com/trimipramine.html
Linkadge
Posted by med_empowered on September 16, 2005, at 20:49:42
In reply to IS reuptake necessary? Surmontil Adaptive changes, posted by linkadge on September 16, 2005, at 20:25:57
Surmontil is a really interesting medication. Apparently, it has some structural similarities to clozapine, which have led to some trials using it as the primary (neuroleptic) treatment for schizophrenia; from what I understand, the trials have been inconclusive (one I read found benefit, but the doses were massive).
Posted by linkadge on September 16, 2005, at 21:18:36
In reply to Re: IS reuptake necessary? Surmontil Adaptive chan, posted by med_empowered on September 16, 2005, at 20:49:42
Yeah it kind of resembles an atypical d2 and 5-ht2 blockade.
I just wish we knew the absolute minimum that was responsable for an AD effect.
There are so many loopholes in the pure-serotonin hypothesis.
Linkadge
This is the end of the thread.
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