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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Michael20073 on June 26, 2005, at 18:37:24
I just recently upped my dosage of Luvox from 100mg to 200mg in an effort to rid myself of some of my OCD symptoms. My doctor also want me to stay on a low dose (500mg) of Depakote.
I read somewhere (it may have even been this site) that Depakote can have a "depressive effect" on someone.
Can anyone shed some more light on this as I have had some problems pulling out of my funk.
Thank you,
Michael
Posted by linkadge on June 26, 2005, at 18:44:56
In reply to Can Depokte make you depressed?, posted by Michael20073 on June 26, 2005, at 18:37:24
It can. Many anticonculsants can exasperate depression. Adding folic acid (1mg) seems to help many people avoid the most bothersome side effects.
Linkadge
Posted by barbaracat on June 27, 2005, at 2:17:25
In reply to Can Depokte make you depressed?, posted by Michael20073 on June 26, 2005, at 18:37:24
I had a bad experience on Depakote and became lethargically depressed and could hardly move or think. It actually was a nice change from the agitated mixed state depression I was in from switching from my normal lithium. But yes, Depakote is known to cause lethargy and depression in some people. I felt much better after getting back on lithium.
> I just recently upped my dosage of Luvox from 100mg to 200mg in an effort to rid myself of some of my OCD symptoms. My doctor also want me to stay on a low dose (500mg) of Depakote.
> I read somewhere (it may have even been this site) that Depakote can have a "depressive effect" on someone.
> Can anyone shed some more light on this as I have had some problems pulling out of my funk.
> Thank you,
> Michael
Posted by Sonya on June 27, 2005, at 11:59:21
In reply to Can Depokte make you depressed?, posted by Michael20073 on June 26, 2005, at 18:37:24
I've been on 1,000mg Depakote; now gradually getting off of it. It makes me lethargic, apathetic and depressed.
Posted by cache-monkey on June 28, 2005, at 0:01:24
In reply to Can Depokte make you depressed?, posted by Michael20073 on June 26, 2005, at 18:37:24
I have mostly anxiety problems, but also low-grade dysthymia that's been known to slip into depression. Depakote made that happen pretty bad for me.
I think that my depressions are dopamine-related (almost exclusively tied to quitting smoking). Depakote increases GABA in the brain which can clamp down on dopamine. This can lead to the apathetic, anergic sort of depression that a couple of other people in this thread have described.
Why are you on the Depakote? Is it mood stabilization or for anxiety? Either it sounds like another drug might be a better choice.
Good luck,
cache-monkey> I just recently upped my dosage of Luvox from 100mg to 200mg in an effort to rid myself of some of my OCD symptoms. My doctor also want me to stay on a low dose (500mg) of Depakote.
> I read somewhere (it may have even been this site) that Depakote can have a "depressive effect" on someone.
> Can anyone shed some more light on this as I have had some problems pulling out of my funk.
> Thank you,
> Michael
This is the end of the thread.
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