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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Dinah on March 3, 2005, at 13:57:41
I continue to believe that my main biological problems result from a disregulation in my cholinergic system. So many physical things seem to point in that direction. Right down to my nose running during orgasm.
But I can't seem to find a drug solution to the problem because all the drugs that affect the cholinergic system also affect adrenaline, which makes sense if I'm understanding what I'm reading. And to be honest, it goes way over my head sometimes. But the systems are closely related, right?
Are they doing any research on drugs in this area?
Posted by linkadge on March 3, 2005, at 16:23:39
In reply to Any research on the cholinergic system?, posted by Dinah on March 3, 2005, at 13:57:41
Thats funny, I was thinking about this today.
Drugs that increase cholinergic transmission, but also tend to increase depression. Anticholinergics have antidepressant effect.
Mania might be due to an underative cholinergic system, and depression due to an overactive cholingic sytstem.
It is called the cholinergic-adrenergic axis.
You can certainly get sole anticholinergics such as cogentin. These have mood brighening effects but can dose dependatly make you dumb.
Linkadge
Posted by MM on March 3, 2005, at 17:15:14
In reply to Re: Any research on the cholinergic system?, posted by linkadge on March 3, 2005, at 16:23:39
Do either of you have any good links for learning about the cholinergic system? I've only recently heard of acetylcholine, and now I can't even remember where or why it was intriguing. I have sneezing fits when I get emotionally overwhelmed instead of crying sometimes (because I just can't cry sometimes). I apologize if I'm a total moron, but I do come to Babble to learn about this stuff.
MM
Posted by Dinah on March 3, 2005, at 18:55:22
In reply to Re: Any research on the cholinergic system? » linkadge, posted by MM on March 3, 2005, at 17:15:14
I have links somewhere, but can't find them. Maybe they're on an old computer. :(
I do have these
http://www.biopsychiatry.com/acetph.htm
http://www.neuropsychiatryreviews.com/aug00/npr_aug00_apathy.html
But I know I keep running across it whenever I research sundry odd things about me. I ran across it with irritable bowel syndrome. I ran across it with rhinosomethingoranother, which is my streaming nose in certain circumstances including migraines. I just keep running across it.
It seems like a promising area to consider.
Posted by Dinah on March 3, 2005, at 18:57:09
In reply to Re: Any research on the cholinergic system?, posted by linkadge on March 3, 2005, at 16:23:39
Hmmm. I wouldn't like dumb. I feel dumb enough as it is.
Posted by MM on March 3, 2005, at 19:43:01
In reply to Re: Any research on the cholinergic system?, posted by Dinah on March 3, 2005, at 18:55:22
Have you considered trying anything else to increase acetylcholine?
http://brain.web-us.com/smartbrain/default.htm#acetylcholine
Posted by Dinah on March 3, 2005, at 22:06:46
In reply to Re: Any research on the cholinergic system? » Dinah, posted by MM on March 3, 2005, at 19:43:01
Well, I'm embarassed to admit it, but I'm failing to understand a key concept. I suspect I'd be one of the negative responders to the physostigmine challenge, but I can't remember if that means that I do worse with a lot of acetylcholine, or too little.
This is the end of the thread.
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