Psycho-Babble Medication Thread 462582

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Klonopin - taking permanently, dosing adjustments

Posted by sdb on February 24, 2005, at 7:23:42

I have used Clonazepam (2mg) 1.5-2h before stressfull situations. With the 2mg Clonazepam I felt very normal during a stressfull event.

1mg Clonazepam controversaly increased the anxiety (sole intake).

The duration of action of Clonazepam is perhaps 6 hours when I take only one pill, thus not permanently. If I would like to have a constant effect during the day, I must take 2x 1mg.

I have never used the Clonazepam longer than some days in low dosages.

I have read that many people start with higher dosages and then they go gradually down to 2.1mg-1mg (see also studies, abstracts). Is it possible that the plasma levels during longterm use elevate and then I could only take 1mg per day and not a splitted dosage of 2mg as I did when I took it only occasionally?

 

Re: Klonopin - taking permanently, dosing adjustments

Posted by awatts on February 24, 2005, at 8:26:33

In reply to Klonopin - taking permanently, dosing adjustments, posted by sdb on February 24, 2005, at 7:23:42

> I have used Clonazepam (2mg) 1.5-2h before stressfull situations. With the 2mg Clonazepam I felt very normal during a stressfull event.
>
> 1mg Clonazepam controversaly increased the anxiety (sole intake).
>
> The duration of action of Clonazepam is perhaps 6 hours when I take only one pill, thus not permanently. If I would like to have a constant effect during the day, I must take 2x 1mg.
>
> I have never used the Clonazepam longer than some days in low dosages.
>
> I have read that many people start with higher dosages and then they go gradually down to 2.1mg-1mg (see also studies, abstracts). Is it possible that the plasma levels during longterm use elevate and then I could only take 1mg per day and not a splitted dosage of 2mg as I did when I took it only occasionally?
>
>
For a constant effect, split dosing (AM and PM) has always worked best for me. If you want to use clonazepam long term, the worst thing you can do is take a single dose only at night.

I currently take 0.25 mg morning and night.

 

Re: Klonopin - taking permanently, dosing adjustme » awatts

Posted by Mildred on February 24, 2005, at 10:39:25

In reply to Re: Klonopin - taking permanently, dosing adjustments, posted by awatts on February 24, 2005, at 8:26:33


If you want to use clonazepam long term, the worst thing you can do is take a single dose only at night.

Why is that? I have been on a single dose at night - .5 mg. It helped me to go to sleep at night, although I have been having some trouble with sleep lately. Not too troubled with anxiety during the day.

 

Re: Klonopin - taking permanently, dosing adjustme

Posted by awatts on February 24, 2005, at 18:28:47

In reply to Re: Klonopin - taking permanently, dosing adjustme » awatts, posted by Mildred on February 24, 2005, at 10:39:25

>
> If you want to use clonazepam long term, the worst thing you can do is take a single dose only at night.
>
> Why is that? I have been on a single dose at night - .5 mg. It helped me to go to sleep at night, although I have been having some trouble with sleep lately. Not too troubled with anxiety during the day.
>
Because, I said "long term use". It can work as a sedative for a few weeks, but after that it usually does nothing to help sleep, and you can suffer minor hangover effects the next day if you don't take some agian in the morning.

If you take half of your dose at night and half in the morning, I bet that your sleep would be no worse, and the anxiety that you are "not too troubled with" during the day will be gone or reduced.

Of course we all react differently to these meds. However, from years of personal experience and from lots of reading, I believe the above is largely true.



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