Psycho-Babble Medication Thread 453566

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memantine update

Posted by emme on February 5, 2005, at 9:26:10


The AD effect is holding at a little over 2 weeks. My gawd I'm grateful to have some relief.

Scott, did your drunken feeling manifest with spacey brain fog and terrible drowsiness? 10 mg is apparently too high for me. I have difficulty tolerating most drugs, so YMMV folks.


 

Re: memantine update » emme

Posted by SLS on February 5, 2005, at 9:42:41

In reply to memantine update, posted by emme on February 5, 2005, at 9:26:10

Hi Emme.

> The AD effect is holding at a little over 2 weeks. My gawd I'm grateful to have some relief.

I received some benefit from memantine that lasted about 2 weeks before disappearing. Let's hope you don't follow the same pattern.

> Scott, did your drunken feeling manifest with spacey brain fog and terrible drowsiness?

I guess you could say that I felt spacey. Everyone uses different words to describe the same things. After a few days at 40mg, I really felt as if I were drunk or stoned.

Is there any trend towards the mitigation of the cognitive changes?


- Scott

 

Re: memantine update » SLS

Posted by emme on February 5, 2005, at 10:48:33

In reply to Re: memantine update » emme, posted by SLS on February 5, 2005, at 9:42:41


> I received some benefit from memantine that lasted about 2 weeks before disappearing. Let's hope you don't follow the same pattern.

Hope springs eternal..... :)

> I guess you could say that I felt spacey. Everyone uses different words to describe the same things. After a few days at 40mg, I really felt as if I were drunk or stoned.

Our experiences may be similar. And this is supposed to be a drug for dementia.....?

> Is there any trend towards the mitigation of the cognitive changes?

Do you mean mitigation of depression-induced cognitive changes, or do you mean fading of memantine-induced spaciness? On the whole, I'd say no to both. I'd say aricept was better for cognition.

I'll see what happens if I'm able to regain some alertness with a lower dose. The relief from depression has been so marked that I'm trying to be patient with the other issues. I wish the half-life was shorter so that I'd get a quicker response to dose changes.

 

Re: memantine update

Posted by calamityjane on February 5, 2005, at 15:04:13

In reply to memantine update, posted by emme on February 5, 2005, at 9:26:10

I am new here, so please verify what med you are refering too.....sorry...thanks :)

 

Re: memantine update » calamityjane

Posted by SLS on February 5, 2005, at 16:02:40

In reply to Re: memantine update, posted by calamityjane on February 5, 2005, at 15:04:13

> I am new here, so please verify what med you are refering to...

Hi.

Memantine goes by the brand name Namenda. It was recently approved for use in treating moderate to severe Alzheimers Dementia. However, it has been used in Germany for over a decade. There, they also use it for Parkinsons Disease and, occasionally, for depression. Technically, memantine is a non-competitive NMDA glutamate receptor antagonist. There is some thought that this drug might also prevent developing tolerance to opioids and stimulants. There is much more reported evidence in the medical literature for the former than the latter.

I hope this helps.


- Scott

 

Re: memantine update

Posted by calamityjane on February 5, 2005, at 16:06:35

In reply to Re: memantine update » calamityjane, posted by SLS on February 5, 2005, at 16:02:40

Yes, thanks, it helped a lot! :)


> > I am new here, so please verify what med you are refering to...
>
> Hi.
>
> Memantine goes by the brand name Namenda. It was recently approved for use in treating moderate to severe Alzheimers Dementia. However, it has been used in Germany for over a decade. There, they also use it for Parkinsons Disease and, occasionally, for depression. Technically, memantine is a non-competitive NMDA glutamate receptor antagonist. There is some thought that this drug might also prevent developing tolerance to opioids and stimulants. There is much more reported evidence in the medical literature for the former than the latter.
>
> I hope this helps.
>
>
> - Scott
>
>
>
>

 

Re: memantine update

Posted by SadDoggie on February 6, 2005, at 3:52:40

In reply to memantine update, posted by emme on February 5, 2005, at 9:26:10

That's great! I should be getting it in a week or so, I hope I have a good response like you. Continued success.


SadDoggie

>
> The AD effect is holding at a little over 2 weeks. My gawd I'm grateful to have some relief.
>
> Scott, did your drunken feeling manifest with spacey brain fog and terrible drowsiness? 10 mg is apparently too high for me. I have difficulty tolerating most drugs, so YMMV folks.
>
>
>
>
>
>
>


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