![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by darkhorse on December 20, 2004, at 8:31:27
Hi,
Anybody tried primodine? its metabolite is supposed to have phenobarbital/Phenobarbitone
Does anybody know equivilant dose for e.g. 250mg primodine to how many phenobarbital mgs?
Thank you,all you experts out there!
Regards,
Adam
Posted by ed_uk on December 20, 2004, at 9:25:17
In reply to Primodine(Mysoline) experience ?, posted by darkhorse on December 20, 2004, at 8:31:27
Hi Adam,
I think that about 15-25% of a dose of primidone is metabolised to phenobarbital. Phenylethylmalonamide is one of the other metabolites of primidone.
I remember that you said you liked phenobarbital. I get the impression that there is less stigma attached to using primidone than phenobarbital, perhaps because some prescribers are unaware that much of the effect of primidone is due to phenobarbital. Are you thinking of taking primidone?
Ed.
PS. Are you in South Africa at the moment?
Posted by darkhorse on December 20, 2004, at 9:47:08
In reply to Re: Primodine(Mysoline) experience ?, posted by ed_uk on December 20, 2004, at 9:25:17
> Hi Adam,
>
> I think that about 15-25% of a dose of primidone is metabolised to phenobarbital. Phenylethylmalonamide is one of the other metabolites of primidone.
>
> I remember that you said you liked phenobarbital. I get the impression that there is less stigma attached to using primidone than phenobarbital, perhaps because some prescribers are unaware that much of the effect of primidone is due to phenobarbital. Are you thinking of taking primidone?
>
> Ed.
>
> PS. Are you in South Africa at the moment?Hi Ed,
I knew you'd be the first to answer! thanx!
Well,I'm in Austria now,and I asked for pheno,but the pharmacist told me is not available and gave me primodine 250mg,so I wanted to know how much phen is inside primodine,like e.g. 250mg = 30mg phen?Unfortunatly I have to leave my PC now,but I'll be back soon....Thank you so much,and awaiting for your opinion about this issue and other questions I have raised in other threads....
Best regards,
Adam.
Posted by ed_uk on December 21, 2004, at 7:49:38
In reply to Re: Primodine(Mysoline) experience ?, posted by darkhorse on December 20, 2004, at 9:47:08
Hi,
Primidone won't be exactly like phenobarbital because it has got other active metabolites as well as phenobarb. As a result, you can't really say that x mg primidone=y mg phenobarb. Also, the amount of phenobarb produced from a fixed dose of primidone will be subject to interindividual variation. With primidone, you're supposed to start with a very low dose (125mg/day) and increase gradually. Apparantly, side effects can be a problem if you increase too fast or initiate treatment with a dose which is too high- this may occur even if you've previously tolerated high doses of phenobarb well. Take care, be cautious! I wouldn't want you to run into any problems :-) Btw, you make it sound like you bought primidone without a prescription. I wouldn't have thought that that would be possible in Austria. Please tell us more.....
Ed.
Posted by darkhorse on December 21, 2004, at 9:01:30
In reply to Re: Primidone (Mysoline), posted by ed_uk on December 21, 2004, at 7:49:38
Hi Ed,
Well,you got me worried about trying primidone...I think am not going to try it...I have plenty of other better benzos to pick from..I think I will return them to the pharmacy.
Well,as for me purchasing medications,it is my kind of job which allows me to buy any medications I want..but I know that you are kind enough for not asking about my type of job(I'm not a doctor).
Regards,
Adam.
Posted by ed_uk on December 21, 2004, at 9:30:11
In reply to Re: Primidone (Mysoline) » ed_uk, posted by darkhorse on December 21, 2004, at 9:01:30
> Well,you got me worried about trying primidone...I think am not going to try it...I have plenty of other better benzos to pick from..I think I will return them to the pharmacy.HI! I wasn't trying to worry you. I just didn't want you to start the primidone at a high dose and then regret it. I know you tolerated high doses of pheno so I was concerned that you might take a really high dose of primidone and 'knock yourself out'. How did pheno compare to a benzo? Did you prefer it?
Are you still happy with bromazepam, alprazolam and lorazepam?
> Well,as for me purchasing medications,it is my kind of job which allows me to buy any medications I want..but I know that you are kind enough for not asking about my type of job(I'm not a doctor).I'm not that nice! It would be good if you'd send me a babblemail and tell me more :-) I will keep your secret, I promise.
.....or maybe you'll remain a darkhorse.Ed.
Posted by darkhorse on December 22, 2004, at 4:29:52
In reply to Re: Primidone (Mysoline), posted by ed_uk on December 21, 2004, at 9:30:11
>
> > Well,you got me worried about trying primidone...I think am not going to try it...I have plenty of other better benzos to pick from..I think I will return them to the pharmacy.
>
> HI! I wasn't trying to worry you. I just didn't want you to start the primidone at a high dose and then regret it. I know you tolerated high doses of pheno so I was concerned that you might take a really high dose of primidone and 'knock yourself out'. How did pheno compare to a benzo? Did you prefer it?
> Are you still happy with bromazepam, alprazolam and lorazepam?I'm happy with my benzos,but as I told you before, from time to time I have this desire to "taste" another benzo/sedative if only for a day or 2 (psychological addiction??).I'm trying hard not to have those ideas but it seems that they are like some form of OCD once I take the pill I feel good and my obsessions fade(For a while)...I know that fluoxetine made this issue vanish ,but the weight gain/apathy/teeth grinding/sexual inhibition is a very high price to pay for such an inconvinient obsession.....
>
>
> > Well,as for me purchasing medications,it is my kind of job which allows me to buy any medications I want..but I know that you are kind enough for not asking about my type of job(I'm not a doctor).
>
> I'm not that nice! It would be good if you'd send me a babblemail and tell me more :-) I will keep your secret, I promise.
> .....or maybe you'll remain a darkhorse.
>
> Ed.Oh! I thought ALL Brits were gentlemen (hehheh)..just joking...some of my best friends are brits!...OK :
First ,I tried to activate this babblemail but did not know how and am too lazy to think and try..
Second,if you help me,I do not think I will tell you more......howevert,I do not know if this is OK to say this here or if this will offend you,but I happen to have 200 pills of Lorazepam 1mg (Temesta)which I do not intend to use and most likley will throw away,or maybe,if you are interested I could send them to you (free of course!)- just a thought......Best regards,
Adam.
>
Posted by ed_uk on December 22, 2004, at 5:32:55
In reply to Re: Primidone (Mysoline) » ed_uk, posted by darkhorse on December 22, 2004, at 4:29:52
>I happen to have 200 pills of Lorazepam 1mg (Temesta)which I do not intend to use and most likley will throw away,or maybe,if you are interested I could send them to you (free of course!)- just a thought......
Hi Adam,
Thank you, they would be useful but we can't discuss sending them or else Dr. Bob will block us from psycho-babble!
Best Regards,
Ed.
PS. You really are a darkhorse aren't you!?
Posted by Dr. Bob on December 22, 2004, at 17:45:50
In reply to Re: Primidone (Mysoline) » ed_uk, posted by darkhorse on December 22, 2004, at 4:29:52
> I do not know if this is OK to say this here or if this will offend you,but I happen to have 200 pills of Lorazepam 1mg (Temesta)which I do not intend to use and most likley will throw away,or maybe,if you are interested I could send them to you (free of course!)- just a thought......
Please do not offer medication directly to others here.
If you or others have questions about this or about posting policies in general, please see the FAQ:
http://www.dr-bob.org/babble/faq.html#illegal
Follow-ups regarding these issues should be redirected to Psycho-Babble Administration. Thanks,
Bob
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.