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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by lacontessa on December 17, 2004, at 22:38:01
I am a new user of Remaron.
I switched from PAxil, to Selexa and although they were both working was having problems with orgasms.OBviously i kinda like having them, so we've just switched to remaron. 30mg.
At bed time.Anybody having problems getting over the drugged feeling....only been on them for 3 days.
Hoping this will alleviate the issues with orgasms.
Anybody else having had problems with celexa and paxil and orgasms.
I am a female. I also gained 10 pounds on the paxil...hoping this won't happen with remaron.
Any information and experiences would be helpful. Any indformation on additional side affects.
Other ideas welcome.
Lacontessa
Posted by King Vultan on December 18, 2004, at 0:25:28
In reply to Remaron - orgasms - celexa - added info wanted, posted by lacontessa on December 17, 2004, at 22:38:01
Unfortunately, Remeron is perhaps the most notorious drug in the antidepressant class for weight gain. Trazodone and nefazodone are (somewhat) similar drugs that do not have the notorious orgasm problems of the SSRIs and also lack Remeron's propensity for inducing weight gain. Trazodone is also quite sedating, while nefazodone is less so, though, still sedating in absolute terms.
Todd
Posted by Larry Hoover on December 18, 2004, at 9:13:06
In reply to Re: Remaron - orgasms - celexa - added info wanted, posted by King Vultan on December 18, 2004, at 0:25:28
> Unfortunately, Remeron is perhaps the most notorious drug in the antidepressant class for weight gain. Trazodone and nefazodone are (somewhat) similar drugs that do not have the notorious orgasm problems of the SSRIs and also lack Remeron's propensity for inducing weight gain. Trazodone is also quite sedating, while nefazodone is less so, though, still sedating in absolute terms.
>
> ToddAnd considering the context of the initial inquiry, Remeron is not devoid of sexual dysfunction problems. They would have you believe that mirtazapine doesn't cause problems, but that's not correct. At least, not if somebody actually asks the recipients of the medication how it affected them sexually.
Lar
J Clin Psychiatry. 2002 Apr;63(4):357-66.Prevalence of sexual dysfunction among newer antidepressants.
Clayton AH, Pradko JF, Croft HA, Montano CB, Leadbetter RA, Bolden-Watson C, Bass KI, Donahue RM, Jamerson BD, Metz A.
Department of Psychiatric Medicine, University of Virginia, Charlottesville 22903, USA. ahc8v@virginia.edu
BACKGROUND: Sexual dysfunction commonly occurs during antidepressant treatment. However, the reported rates of sexual dysfunction vary across antidepressants and are typically underreported in product literature. The objectives of this study were (1) to estimate the prevalence of sexual dysfunction among patients taking newer antidepressants (bupropion immediate release [IR], bupropion sustained release [SR], citalopram, fluoxetine, mirtazapine, nefazodone, paroxetine, sertraline, venlafaxine, and venlafaxine extended release [XR]) and (2) to compare physician-perceived with patient-reported prevalence rates of antidepressant-associated sexual dysfunction. METHOD: This cross-sectional, observational study was conducted in 1101 U.S. primary care clinics. Adult outpatients (4534 women and 1763 men) receiving antidepressant monotherapy were enrolled. The prevalence of sexual dysfunction was measured using the Changes in Sexual Functioning Questionnaire. RESULTS: In the overall population, bupropion IR (22%) and SR (25%) and nefazodone (28%) were associated with the lowest risk for sexual dysfunction, whereas selective serotonin reuptake inhibitor (SSRI) antidepressants, mirtazapine, and venlafaxine XR were associated with higher rates (36%-43%). In a prospectively defined subpopulation unlikely to have predisposing factors for sexual dysfunction, the prevalence of sexual dysfunction ranged from 7% to 30%, with the odds of having sexual dysfunction 4 to 6 times greater with SSRIs or venlafaxine XR than with bupropion SR. Physicians consistently underestimated the prevalence of antidepressant-associated sexual dysfunction. CONCLUSION: Ours is the first study to assess sexual dysfunction across the newer antidepressants using consistent methodology and a validated rating scale. Overall, SSRIs and venlafaxine XR were associated with higher rates of sexual dysfunction than bupropion or nefazodone. Because antidepressant-associated sexual dysfunction is considerably underestimated by physicians, greater recognition and education are imperative when prescribing antidepressant treatment.
J Clin Psychiatry. 2001;62 Suppl 3:10-21.
Comment in:
J Clin Psychiatry. 2002 Feb;63(2):168.Incidence of sexual dysfunction associated with antidepressant agents: a prospective multicenter study of 1022 outpatients. Spanish Working Group for the Study of Psychotropic-Related Sexual Dysfunction.
Montejo AL, Llorca G, Izquierdo JA, Rico-Villademoros F.
University Hospital of Salamanca, Psychiatric Teaching Area, University of Salamanca, School of Medicine, Spain. angelluis.montejo@globalmed.es
BACKGROUND: Antidepressants, especially selective serotonin reuptake inhibitors (SSRIs), venlafaxine, and clomipramine, are frequently associated with sexual dysfunction. Other antidepressants (nefazodone, mirtazapine, bupropion, amineptine, and moclobemide) with different mechanisms of action seem to have fewer sexual side effects. The incidence of sexual dysfunction is underestimated, and the use of a specific questionnaire is needed. METHOD: The authors analyzed the incidence of antidepressant-related sexual dysfunction in a multicenter, prospective, open-label study carried out by the Spanish Working Group for the Study of Psychotropic-Related Sexual Dysfunction. The group collected data from April 1995 to February 2000 on patients with previously normal sexual function who were being treated with antidepressants alone or antidepressants plus benzodiazepines. One thousand twenty-two outpatients (610 women, 412 men; mean age = 39.8 +/- 11.3 years) were interviewed using the Psychotropic-Related Sexual Dysfunction Questionnaire, which includes questions about libido, orgasm, ejaculation, erectile function, and general sexual satisfaction. RESULTS: The overall incidence of sexual dysfunction was 59.1% (604/1022) when all antidepressants were considered as a whole. There were relevant differences when the incidence of any type of sexual dysfunction was compared among different drugs: fluoxetine, 57.7% (161/279); sertraline, 62.9% (100/159); fluvoxamine, 62.3% (48/77); paroxetine, 70.7% (147/208); citalopram, 72.7% (48/66); venlafaxine, 67.3% (37/55); mirtazapine, 24.4% (12/49); nefazodone, 8% (4/50); amineptine, 6.9% (2/29); and moclobemide, 3.9% (1/26). Men had a higher frequency of sexual dysfunction (62.4%) than women (56.9%), although women had higher severity. About 40% of patients showed low tolerance of their sexual dysfunction. CONCLUSION: The incidence of sexual dysfunction with SSRIs and venlafaxine is high, ranging from 58% to 73%, as compared with serotonin-2 (5-HT2) blockers (nefazodone and mirtazapine), moclobemide, and amineptine.
Posted by lacontessa on December 18, 2004, at 16:46:50
In reply to Re: Remaron - orgasms - celexa - added info wanted » King Vultan, posted by Larry Hoover on December 18, 2004, at 9:13:06
Any women out there with similar experiences and suggestions of medication that would have a lesser impact on orgasm but help with anxiety and depression?????
Posted by francesco on December 18, 2004, at 20:50:02
In reply to Re: Remaron - orgasms - celexa - added info wanted, posted by lacontessa on December 18, 2004, at 16:46:50
Remeron will not help you to lose weight, this is sure. Even it's not necessarily free of sexual side effect if I were in your shoes I will wait to see if they actually happen. There a just a bunch of drugs that are said not to cause sexual side effects, or to cause them in a less percentage of cases. Wellbutrin, Remeron and Serzone. I have read that the 5% of women who take Anafranil have an orgasm every time they yawn. So, if you feel lucky, it may be worth of a trial ;-)
Posted by cherylann on December 19, 2004, at 12:38:09
In reply to Remaron - orgasms - celexa - added info wanted, posted by lacontessa on December 17, 2004, at 22:38:01
Hi there,
Remeron has had some side effects for me that will ultimately force me to stop it.
With SSRI's the desire was still there, just couldn't complete the job. With Remeron, I can complete the job, but the desire is absolutely gone. Add to this the weight gain.The one drug that I used in the beginning that worked so well and actually increased my desire and ability was Doxepin. Unfortunately, after the doc decided I didn't need it anymore, then put me back on after symptoms returned, it didn't work.
Best wishes,
cherylann
Posted by lacontessa on December 19, 2004, at 22:19:19
In reply to Re: Remaron - orgasms - celexa - added info wanted » lacontessa, posted by cherylann on December 19, 2004, at 12:38:09
Actually I did try Wellbutrin - it was horrible - I GOT MORE DEPRESSED - crying uncontrollably - thinking horrible thoughts -and the orgasms didn't even cross my mind - let alone attempting them. So Wellbutrin was out.
The only SSRI's other than that that I had tried were Celexa and Paxil - both with similar side affects - difficulty to orgasm.
I haven't heard of the last one noted by Cherylann but will look into it - So far i'm not impressed with Remaron - and i have also had puffy eyes - for hours after awakening anybody experiencing that on SSRI's?
Mostly wtih Wellbutrin and now with Remaron - perhaps because of too much sleep on remaron?
This is the end of the thread.
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