![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by sabre on October 13, 2004, at 1:37:04
After using Moclobemide for a week - 150mg in one morning dose, I increased to 2 doses/day for a total of 300mg for a couple of days. Felt awful...depressed, stuffed and antisocial. Couldn't get off the couch or out from under the doona.
Cut the dose back to 75mg x twice a day. Interestingly, this was more energising than the single 150mg dose/day. I even experienced some insomnia whereas I hadn't felt it at 150 or 300...quite the opposite in fact.
The side effects of palpitations and burping were annoying. I read on some cardiac sites that some people experience irritation of the vagal nerve through acid reflux or gas pressure that can cause the palpitations. My heart rate wasn't elevated. Just seemed to miss a beat and flop approx every 10 beats.
In addition when I tried to race (running) the vasodilation effect seemed to create a lag effect in the first couple of kms. Beyond that it was okay.
I found the low dose made me more happy but I started experiencing more panic at the same time. Strange. I felt like my body was revving...sweaty armpits and increased git effects.Decided to go off it a couple of days ago because I just didn't feel like it was going to help the social anxiety. The studies I have looked at that helped SA used high doses ie at least 450mg. I think I'd be comatose on this.
This therapeutic dose business just doesn't make sense to me. How can everyone have the same td?
Body weight;lean muscle mass; sex; age; metabolism; psyche conditions all vary from person to person. I have found now that I get a strong effect from 25% of the recommended therapeutic dose.Not sure what to do now. I found an online book written by a pyschiatrist who 'cured' her own depression by trying supplements of vit c, vit B, tryptophan and tyrosine. I've started on the
vitamins and have got some tryptophan to use.Has anyone tried this program?
http://www.thewayup.com/ebook/f/TheWayUp.pdfOver the last few days I've been relying on the Propranolol and feel depressed but then again I've probably been mucking around too much with the Moclo experimentation.
I just feel like the serotonin and noradrenaline might not be the answer for SA, for me anyway.sabre
Posted by SLS on October 13, 2004, at 7:55:57
In reply to Moclobemide again, posted by sabre on October 13, 2004, at 1:37:04
Hi.
I'm sorry moclobemide didn't work out for you.
I have bipolar depression. Moclobemide exacerbated my depression to the point that I remained curled up on a couch in the fetal position for days. I have never felt worse. Although this is an unusual reaction to this drug, I am not unique in this regard.
- Scott
Posted by sabre on October 15, 2004, at 19:03:33
In reply to Re: Moclobemide again, posted by SLS on October 13, 2004, at 7:55:57
Thanks Scott
It has come at a bad time. I have been struggling to find something in a hurry. I had an interview for medical school yesterday and I after managing to pass the gamsat exam (like MCAT) I ended up pulling out two days beforehand. I knew I couldn't face the interview and the PBL method of teaching now would have had killed me. I feel a failure.
sabre
Posted by Jasmineneroli on October 16, 2004, at 0:10:11
In reply to Re: Moclobemide again, posted by sabre on October 15, 2004, at 19:03:33
I hated Moclobemide. It made feel very ill and tired at all doses from 150mg up to 450mg. Extremely bad migraine headaches, general flu-like symptoms, depression, lethargy. Aaagh! One of the worst meds for me.
It's supposed to be a "clean" drug with very few side effects. I guess we're just unlucky :).Don't feel like you've failed. You must have done awesomely to pass the exam, considering your condition and the drug trial(s). Med. school is a huge demand and committment. Once you have sorted out the right medication and have stabilized, you can try again!!!
Maybe this is not the right time for med school. It's the right time to keep working at an answer for your SA.
Very best wishes
Jas
Posted by sabre on October 16, 2004, at 0:25:40
In reply to Re: Moclobemide again » sabre, posted by Jasmineneroli on October 16, 2004, at 0:10:11
Thanks for the kind words, Jasmineneroli.
I know it's not the end of the world but right now it feels like one of those depressing milestones in life.I just can't imagine a miraculous drug that will change all this and with each drug you try you lose a bit of hope.
I'm looking at giving Reboxetine a try next. You never know.
Thanks
sabre
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.