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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by TomV on October 7, 2004, at 21:23:44
Since I'm about to start Parnate, I got to thinking why I chose it over Nardil. Nardil on paper seems like the better drug to try for me, but the side effect profile seems more bothersome. I have significiant depression, anxiety, and some social phobia, and I have a feeling Nardil has a better chance of working. I've taken many of the newer and older generation drugs, with very little success. But I'm thinking down the road a bit here.
What I'm thinking is, if Parnate only works partially, perhaps I can add Nardil later?Perhaps I can work toward a one-half standard dosage of both? Does this sound like a good idea? Has this worked for anyone?
Maybe Parnate will do the trick but I'm getting ready for contingencies, and this is one of them that I've given some thougt to.
Tom
Posted by utopizen on October 7, 2004, at 22:04:00
In reply to Ok to take Parnate and Nardil together?, posted by TomV on October 7, 2004, at 21:23:44
Um, let's be a bit open here, your doc is unlikely to do this. He must confirm to APA standards, which, as my doc explained to me, says he must first optimize one drug before moving on to others. Obviously, this often doesn't happen, but that doesn't make it okay.
I hate this, I know, I'm suffering with severe social anxiety, and my professors and classmates look extremely concerned by the expressions on their faces as I try to talk in such a stressed and anxious way. It pains me. I don't have Klonopin because I've been going to this doc and that and my last one wouldn't let me continue it and my present one will but wants me to try Lexapro out for awhile before adding it. (I know, he won't even give me it PRN, but ah well).
Posted by King Vultan on October 7, 2004, at 22:56:47
In reply to Ok to take Parnate and Nardil together?, posted by TomV on October 7, 2004, at 21:23:44
> Since I'm about to start Parnate, I got to thinking why I chose it over Nardil. Nardil on paper seems like the better drug to try for me, but the side effect profile seems more bothersome. I have significiant depression, anxiety, and some social phobia, and I have a feeling Nardil has a better chance of working. I've taken many of the newer and older generation drugs, with very little success. But I'm thinking down the road a bit here.
>
> What I'm thinking is, if Parnate only works partially, perhaps I can add Nardil later?Perhaps I can work toward a one-half standard dosage of both? Does this sound like a good idea? Has this worked for anyone?
>
> Maybe Parnate will do the trick but I'm getting ready for contingencies, and this is one of them that I've given some thougt to.
> Tom
Don't even think about mixing these two drugs, as you run a significant risk of suffering a hypertensive crisis, and a two week washout period should be allowed switching between them. There is a report from 1984 of two patients being switched directly from Nardil to Parnate with no washout period. One suffered a hypertensive crisis and the other a stroke. I know that people have successfully switched with no washout period, and perhaps people even have managed to take these two drugs together, but I think it's an exceedingly bad idea.Todd
Posted by sfy on October 7, 2004, at 23:09:31
In reply to Ok to take Parnate and Nardil together?, posted by TomV on October 7, 2004, at 21:23:44
> Since I'm about to start Parnate, I got to thinking why I chose it over Nardil. Nardil on paper seems like the better drug to try for me, but the side effect profile seems more bothersome. I have significiant depression, anxiety, and some social phobia, and I have a feeling Nardil has a better chance of working. I've taken many of the newer and older generation drugs, with very little success. But I'm thinking down the road a bit here.
Having once been on Nardil (and currently contemplating Parnate), I thought that the side effect profiles were similar. If anything, I was under the impression that there's a higher risk of the cheese effect and hypertensive crisis with Parnate than with Nardil. And Parnate, being more activating, makes some people more anxious.
Posted by TomV on October 8, 2004, at 8:05:41
In reply to Re: Ok to take Parnate and Nardil together? » TomV, posted by sfy on October 7, 2004, at 23:09:31
> > Since I'm about to start Parnate, I got to thinking why I chose it over Nardil. Nardil on paper seems like the better drug to try for me, but the side effect profile seems more bothersome. I have significiant depression, anxiety, and some social phobia, and I have a feeling Nardil has a better chance of working. I've taken many of the newer and older generation drugs, with very little success. But I'm thinking down the road a bit here.
>
> Having once been on Nardil (and currently contemplating Parnate), I thought that the side effect profiles were similar. If anything, I was under the impression that there's a higher risk of the cheese effect and hypertensive crisis with Parnate than with Nardil. And Parnate, being more activating, makes some people more anxious.Nardil's profile shows more weight gain & sexual dysfunction, two big no-no's for me. I am aware of the higher risk of the cheese effect with Parnate (which I can control with strict adherence to the diet), and it being more activating, which is a slightly less big no-no. So on paper, I'm basically stuck. But then again, all these drugs, on paper, look like life savers, which is hardly the case...
Tom
Posted by ace on October 10, 2004, at 0:16:59
In reply to Re: Ok to take Parnate and Nardil together?, posted by King Vultan on October 7, 2004, at 22:56:47
> > Since I'm about to start Parnate, I got to thinking why I chose it over Nardil. Nardil on paper seems like the better drug to try for me, but the side effect profile seems more bothersome. I have significiant depression, anxiety, and some social phobia, and I have a feeling Nardil has a better chance of working. I've taken many of the newer and older generation drugs, with very little success. But I'm thinking down the road a bit here.
> >
> > What I'm thinking is, if Parnate only works partially, perhaps I can add Nardil later?Perhaps I can work toward a one-half standard dosage of both? Does this sound like a good idea? Has this worked for anyone?
> >
> > Maybe Parnate will do the trick but I'm getting ready for contingencies, and this is one of them that I've given some thougt to.
> > Tom
>
>
> Don't even think about mixing these two drugs, as you run a significant risk of suffering a hypertensive crisis, and a two week washout period should be allowed switching between them.I disagree. I have never had any more than a two day washout on many occassions between the two, and suffered NO ill effetcs. Furthermore that study you were refering to was negligent in the fact that it never stated what, if any, other drugs these sufferes have taken.
I believe Parnat + Nardil should be safe together. There is one anecdote of it being fine. I wouldn't do it myself but, but I can't see any theoretical danger....
There is a report from 1984 of two patients being switched directly from Nardil to Parnate with no washout period. One suffered a hypertensive crisis and the other a stroke. I know that people have successfully switched with no washout period, and perhaps people even have managed to take these two drugs together, but I think it's an exceedingly bad idea.
>
> ToddSorry to disagree Todd, but that's life!!
Cya,
Ace!
This is the end of the thread.
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