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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by ace on September 30, 2004, at 0:28:36
Due to its 5HT stimulation, Im thinking of using amitriptyline low dose with Nardil....
i've read before the combo is safe.....,
"MAOI: Adverse Effects (Perry, Paul.) 1996 "can anyone add anything??
Ace
Posted by SLS on September 30, 2004, at 8:06:10
In reply to NARDIL + AMITRIPTYLINE -- safe????, posted by ace on September 30, 2004, at 0:28:36
> Due to its 5HT stimulation, Im thinking of using amitriptyline low dose with Nardil....
>
> i've read before the combo is safe.....,
>
>
>
> "MAOI: Adverse Effects (Perry, Paul.) 1996 "
>
> can anyone add anything??
>
>
> Ace
A low dosage might be OK.I experienced what I believe were the beginnings of serotonin syndrome when I added nortriptyline 50mg with Nardil 75mg. The symptoms were severe hypotension and an altered status type mild delirium. Amitriptyline is more serotonergic than is nortriptyline, so I would proceed with caution. Perhaps you will not be as sensitive to such a combination as I was. You might want to target 25mg initially.
- Scott
Posted by SLS on September 30, 2004, at 8:08:48
In reply to Re: NARDIL + AMITRIPTYLINE -- safe????, posted by SLS on September 30, 2004, at 8:06:10
> > Due to its 5HT stimulation, Im thinking of using amitriptyline low dose with Nardil....
> >
> > i've read before the combo is safe.....,
> >
> >
> >
> > "MAOI: Adverse Effects (Perry, Paul.) 1996 "
> >
> > can anyone add anything??
> >
> >
> > Ace
>
>
> A low dosage might be OK.
>
> I experienced what I believe were the beginnings of serotonin syndrome when I added nortriptyline 50mg with Nardil 75mg. The symptoms were severe hypotension and an altered status type mild delirium. Amitriptyline is more serotonergic than is nortriptyline, so I would proceed with caution. Perhaps you will not be as sensitive to such a combination as I was. You might want to target 25mg initially.
I don't believe that such reactions are as likely when using dosages of Nardil of 45mg or less, so when you review the literature, take note of the dosage used in such combinations.
- Scott
Posted by Sad Panda on September 30, 2004, at 10:25:55
In reply to NARDIL + AMITRIPTYLINE -- safe????, posted by ace on September 30, 2004, at 0:28:36
> Due to its 5HT stimulation, Im thinking of using amitriptyline low dose with Nardil....
>
> i've read before the combo is safe.....,
>
>
>
> "MAOI: Adverse Effects (Perry, Paul.) 1996 "
>
> can anyone add anything??
>
>
> Ace
>
>Borderline. I would test the water with Nort first. You may have to drop Zyprexa if you try Amitriptyline because both are potent M1 blockers.
Cheers,
Paul.
This is the end of the thread.
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