Psycho-Babble Medication Thread 341742

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MAOI's and Vivid Nightmares

Posted by matt66 on April 30, 2004, at 9:41:00

I'm on 30mg Marplan, working great after five years of various trials of anything and everything. I'm grateful for each new day, however, I'm experiencing absolutely horrendous nightmares which are so increadibly real, I can't even begin to explain. In addition, I'm on Seroquel for sleep (500mg's), and am unable to wake up, even as I feel my body writhing and shaking in terror.

All my nightmares involve me being devastatingly depressed again, in a constant state of panic, and somehow sensing that I'll never be able to feel better again. It's absolutely dreadful. Are these post-traumatic stress symptoms?-(my four years in college were spent in my dorm room in bed, increadibly depressed and terrified of people. I wasn't eating, sleeping, etc. Basically not functioning, and suffering terribly every day for four years).

Any similar experiences? What do you suggest? Should I up the dose of the Marplan? What's the highest dose of Marplan you've heard of someone taking? (I've taken monster doses of tricyclics, ssri's, and maoi's before and didn't have many bad side effects to speak of, so I am tolerant of high doses).

Thank you,
Matt

 

Re: MAOI's and Vivid Nightmares

Posted by djmmm on April 30, 2004, at 12:33:19

In reply to MAOI's and Vivid Nightmares, posted by matt66 on April 30, 2004, at 9:41:00

> I'm on 30mg Marplan, working great after five years of various trials of anything and everything. I'm grateful for each new day, however, I'm experiencing absolutely horrendous nightmares which are so increadibly real, I can't even begin to explain. In addition, I'm on Seroquel for sleep (500mg's), and am unable to wake up, even as I feel my body writhing and shaking in terror.
>
> All my nightmares involve me being devastatingly depressed again, in a constant state of panic, and somehow sensing that I'll never be able to feel better again. It's absolutely dreadful. Are these post-traumatic stress symptoms?-(my four years in college were spent in my dorm room in bed, increadibly depressed and terrified of people. I wasn't eating, sleeping, etc. Basically not functioning, and suffering terribly every day for four years).
>
> Any similar experiences? What do you suggest? Should I up the dose of the Marplan? What's the highest dose of Marplan you've heard of someone taking? (I've taken monster doses of tricyclics, ssri's, and maoi's before and didn't have many bad side effects to speak of, so I am tolerant of high doses).
>
> Thank you,
> Matt

Typically MAOIs prevent nightmares (via suppression of the REM stage), however nightmares are common when discontinuing MAOIs. Seroquel OFTEN cause nightmares...sometimes a dosage adjustment (lowering) can help.

 

Re: MAOI's and Vivid Nightmares

Posted by ace on April 30, 2004, at 23:28:03

In reply to Re: MAOI's and Vivid Nightmares, posted by djmmm on April 30, 2004, at 12:33:19

> > I'm on 30mg Marplan, working great after five years of various trials of anything and everything. I'm grateful for each new day, however, I'm experiencing absolutely horrendous nightmares which are so increadibly real, I can't even begin to explain. In addition, I'm on Seroquel for sleep (500mg's), and am unable to wake up, even as I feel my body writhing and shaking in terror.
> >
> > All my nightmares involve me being devastatingly depressed again, in a constant state of panic, and somehow sensing that I'll never be able to feel better again. It's absolutely dreadful. Are these post-traumatic stress symptoms?-(my four years in college were spent in my dorm room in bed, increadibly depressed and terrified of people. I wasn't eating, sleeping, etc. Basically not functioning, and suffering terribly every day for four years).
> >
> > Any similar experiences? What do you suggest? Should I up the dose of the Marplan? What's the highest dose of Marplan you've heard of someone taking? (I've taken monster doses of tricyclics, ssri's, and maoi's before and didn't have many bad side effects to speak of, so I am tolerant of high doses).
> >
> > Thank you,
> > Matt
>
> Typically MAOIs prevent nightmares (via suppression of the REM stage), however nightmares are common when discontinuing MAOIs. Seroquel OFTEN cause nightmares...sometimes a dosage adjustment (lowering) can help.


I agree with Djmmm. Its unlikely an MAOI causes any nightmares...but they can cause night time myoclonus and early awakenings...

I believe it is the Seroquel....Zyprexa caused nightmares in me until I took my dose earlier (7pm)

Im not a big fan of Seroquel...I believe EPS is much more common with this drug, as by reading many anecdotes on it...

Good luck

Ace

 

Re: MAOI's and Vivid Nightmares » matt66

Posted by Sad Panda on May 1, 2004, at 2:46:41

In reply to MAOI's and Vivid Nightmares, posted by matt66 on April 30, 2004, at 9:41:00

> I'm on 30mg Marplan, working great after five years of various trials of anything and everything. I'm grateful for each new day, however, I'm experiencing absolutely horrendous nightmares which are so increadibly real, I can't even begin to explain. In addition, I'm on Seroquel for sleep (500mg's), and am unable to wake up, even as I feel my body writhing and shaking in terror.
>
> All my nightmares involve me being devastatingly depressed again, in a constant state of panic, and somehow sensing that I'll never be able to feel better again. It's absolutely dreadful. Are these post-traumatic stress symptoms?-(my four years in college were spent in my dorm room in bed, increadibly depressed and terrified of people. I wasn't eating, sleeping, etc. Basically not functioning, and suffering terribly every day for four years).
>
> Any similar experiences? What do you suggest? Should I up the dose of the Marplan? What's the highest dose of Marplan you've heard of someone taking? (I've taken monster doses of tricyclics, ssri's, and maoi's before and didn't have many bad side effects to speak of, so I am tolerant of high doses).
>
> Thank you,
> Matt
>

I would try Remeron or dirt cheap Doxepin. Taking Seroquel is a bit excessive just for sleep.

Cheers,
Panda.

 

Re: MAOI's and Vivid Nightmares

Posted by cybercafe on May 1, 2004, at 8:05:21

In reply to Re: MAOI's and Vivid Nightmares, posted by djmmm on April 30, 2004, at 12:33:19

> Typically MAOIs prevent nightmares (via suppression of the REM stage), however nightmares are common when discontinuing MAOIs. Seroquel OFTEN cause nightmares...sometimes a dosage adjustment (lowering) can help.

ummm what effect does suppression of REM stage have on a person?

 

Re: MAOI's and Vivid Nightmares

Posted by djmmm on May 1, 2004, at 17:29:25

In reply to Re: MAOI's and Vivid Nightmares, posted by cybercafe on May 1, 2004, at 8:05:21

> > Typically MAOIs prevent nightmares (via suppression of the REM stage), however nightmares are common when discontinuing MAOIs. Seroquel OFTEN cause nightmares...sometimes a dosage adjustment (lowering) can help.
>
> ummm what effect does suppression of REM stage have on a person?
>

For me, I experience REM rebound during the day...sleep attacks (similar to narcolepsy), and VIVID nightmares if I skip a dose of Nardil.


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