![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Janelle on March 12, 2004, at 15:53:02
Seroquel is losing its efficacy as a sleep aid for me and I'm thinking of asking my pdoc next appointment to take me off it and switch to Trazadone. However, I know a few people who say they have awful hangovers in the morning from Trazadone -- I'd like to hear from anyone here who has taken or is taking Trazadone for sleep? What dosage is effective for you and did or do you have hangovers the next day? Thanks!
Posted by Tony P on March 12, 2004, at 17:21:23
In reply to TRAZADONE hangover??, posted by Janelle on March 12, 2004, at 15:53:02
> Seroquel is losing its efficacy as a sleep aid for me and I'm thinking of asking my pdoc next appointment to take me off it and switch to Trazadone. However, I know a few people who say they have awful hangovers in the morning from Trazadone -- I'd like to hear from anyone here who has taken or is taking Trazadone for sleep? What dosage is effective for you and did or do you have hangovers the next day? Thanks!
-------------------------Initially, Trazadone 50 mg was quite effective and natural-feeling; it just gave me a slight hangover. I eventually had to escalate to 100-150 mg, which definitely made it hard to get out bed after 8 hrs. There seems to be a fair bit of individual variation on this - I have a friend who took it for years with no hangover problem.
It may depend on the state of your liver, and what other meds you take. Trazadone is (I understand) metabolized by the same enzyme that looks after some common OTC's such as tylenol and dextromethorphan, as well as some Rx's, so I suppose there might be some competition slowing the clearance rate.
Tony P
Posted by joebob on March 12, 2004, at 19:26:44
In reply to TRAZADONE hangover??, posted by Janelle on March 12, 2004, at 15:53:02
no problems......it is the best that i have used
no hangover to speak of, if your liver is weak, use supplements like silymarin and ala to build it up....
best
Posted by Patient on March 14, 2004, at 13:36:59
In reply to TRAZADONE hangover??, posted by Janelle on March 12, 2004, at 15:53:02
Hi,
I've found trazodone to be an excellent sleep aid. I have taken it alone, as well as while taking an SSRI, and an SSRI with Depakote. Either way, I found the usual dose range of 25mg to 50mg for insomnia to be too much for me, especially 50mg. Fifty mgs. also resulted in stuffy nose and dry mouth, enough to where I couldn't really sleep for two hours after taking it at bedtime.
I reduced to 25mg and this worked just as well, with less nose stuffiness and dry mouth. Even better, 12.5mg worked just as well, with no nose stuffiness or dry mouth. As with melatonin, if you find you are still drowsy in the morning, then reduce the dosage. Who'd have thought that 12.5 mg. would have helped me sleep well, but it did!
Posted by shadows721 on March 14, 2004, at 22:53:22
In reply to Re: Trazodone hangover? Low dose reduces hangover, posted by Patient on March 14, 2004, at 13:36:59
Have any of you found that the trazodone lowered your blood pressure?
I have tried trazodone and serquel. Both work a little bit for sleep. I have tried them together and I am guaranteed to sleep without awakening. But, I tend to sleep for 14 hours straight. My blood pressure is 88/67. I feel half dead. I am very irritable the next day too.
Posted by Patient on March 15, 2004, at 14:15:42
In reply to Re: Trazodone low blood pressure, posted by shadows721 on March 14, 2004, at 22:53:22
Hi,
Yes, it can cause low blood pressure-when I first took it as a sole antidepressant (25mg three times a day) it would cause dizziness upon standing up or turning quickly-typical sign of low blood pressure. Trazodone can cause mild adrenal insufficiency with one of its symptoms being low blood pressure. Since low blood pressure isn't normal and can cause problems, it is wise to try to fix the problem.
You can try lowering trazodone dose, especially if you are feeling sleepy most of the day. It might help reduce the irritability as well. Quetiapine (Seroquel) can cause low blood pressure as well. With both drugs, they especially cause low blood pressure during early treatment, so one should increase dose gradually. I found this true with trazodone-after a few weeks I no longer became dizzy.
One of the best cures for low blood pressure is salt. It's a misconception that salt is bad for everyone-excessive salt can create high blood pressure in SOME people. Using a moderate amount of salt is perfectly healthy--I use sea salt because it contains naturally occuring mixture of salt and minerals. Also, a quality multi-vitamin and mineral complex, with at least a 25mg to 50mg ratio of the vitamin B-complex-is helpful as well.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.