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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by lelebug on February 23, 2004, at 7:58:07
I have read previous posts that have to do with this, but I have a few questions that I couldn't find answers to. Please let me know if anyone has info on this!!!
I am currently taking 300mg of Wellbutrin and 10mg of Lexapro. I do not feel depressed any more. I may experience depression for one day. My anxiety has gone down quit a bit also. However the old nasty side effect of not being able to achieve orgasim is what I am fighting currently. I am going to ask my Dr about adding Buspar. I was wondering if those of you who have used this to augment this s/e could give me some details? Any and all details would be welcomed!! How long did it take to start working? Was it a significant improvement? How else did Buspar effect you? Will it be more relaxing?
I have done research on this and I have found that Buspar is suppose to take the levels of seratonine and other chemicals down. Won't this interfere with my SSRI? Isn't the point of the SSRI to up my levels of seratonine! I'm a bit confused about this.
Posted by HIBA on February 23, 2004, at 22:07:47
In reply to Adding Buspar for Sexual Side Effects-PLEASE HELP!, posted by lelebug on February 23, 2004, at 7:58:07
Buspar is used to treat some of the sexual dysfunction caused by SSRIs. If you believe in anecdotes it may work. Buspar itself is a mild pro-sexual substance. It may work instantly for some, but can take as long as two weeks to make any difference in some individuals. Buspar can cause black mood, irritability and many uncomfortable feelings. But if you are ready to tolerate them all take 10mg twice or thrice daily for a couple of weeks and see if there is any improvment. I hope it may work
HIBA
Posted by krybrahaha on February 24, 2004, at 0:18:42
In reply to Adding Buspar for Sexual Side Effects-PLEASE HELP!, posted by lelebug on February 23, 2004, at 7:58:07
> I have read previous posts that have to do with this, but I have a few questions that I couldn't find answers to. Please let me know if anyone has info on this!!!
>
> I am currently taking 300mg of Wellbutrin and 10mg of Lexapro. I do not feel depressed any more. I may experience depression for one day. My anxiety has gone down quit a bit also. However the old nasty side effect of not being able to achieve orgasim is what I am fighting currently. I am going to ask my Dr about adding Buspar. I was wondering if those of you who have used this to augment this s/e could give me some details? Any and all details would be welcomed!! How long did it take to start working? Was it a significant improvement? How else did Buspar effect you? Will it be more relaxing?
>
> I have done research on this and I have found that Buspar is suppose to take the levels of seratonine and other chemicals down. Won't this interfere with my SSRI? Isn't the point of the SSRI to up my levels of seratonine! I'm a bit confused about this.
I take 300 mgs of Luvox and noticed I couldnt have an orgasm. My P-doc put me on Buspar 10 mgs twice daily----it took about 3 weeks, but, ya it works great. My sexual level is right back to where it was.What SSRI's do is raise serotonin throughout your whole brain. Buspar does decrease serotonin, but the receptor it reduces it at has to do with the side effect of sexual dysfunction, so it works perfectly. This is primarily the receptor in which if it has too much serotonin can cause ssri side effects like anxiety, and sexual dysfunction.
Posted by Questionmark on February 25, 2004, at 0:57:03
In reply to Re: Adding Buspar for Sexual Side Effects-YES!!!!!, posted by krybrahaha on February 24, 2004, at 0:18:42
> > I have read previous posts that have to do with this, but I have a few questions that I couldn't find answers to. Please let me know if anyone has info on this!!!
> >
> > I am currently taking 300mg of Wellbutrin and 10mg of Lexapro. I do not feel depressed any more. I may experience depression for one day. My anxiety has gone down quit a bit also. However the old nasty side effect of not being able to achieve orgasim is what I am fighting currently. I am going to ask my Dr about adding Buspar. I was wondering if those of you who have used this to augment this s/e could give me some details? Any and all details would be welcomed!! How long did it take to start working? Was it a significant improvement? How else did Buspar effect you? Will it be more relaxing?
> >
> > I have done research on this and I have found that Buspar is suppose to take the levels of seratonine and other chemicals down. Won't this interfere with my SSRI? Isn't the point of the SSRI to up my levels of seratonine! I'm a bit confused about this.
>
>
> I take 300 mgs of Luvox and noticed I couldnt have an orgasm. My P-doc put me on Buspar 10 mgs twice daily----it took about 3 weeks, but, ya it works great. My sexual level is right back to where it was.
>
> What SSRI's do is raise serotonin throughout your whole brain. Buspar does decrease serotonin, but the receptor it reduces it at has to do with the side effect of sexual dysfunction, so it works perfectly. This is primarily the receptor in which if it has too much serotonin can cause ssri side effects like anxiety, and sexual dysfunction.i don't believe that's true. The 5-HT2A receptor is serotonin receptor most implicated in the cause of sexual dysfunction. i think Buspar primarily only acts on 5-HT1A receptors (of the 5-HT receptors, that is). It is most likely its actions on the DA2 and alpha-2 adrenergic receptors that is responsible for its alleviation of sexual problems. i'm still really confused about the overall results of its 5-HT1A effects though-- as far as affective ANd sexual effects. i don't get it.
Posted by krybrahaha on February 25, 2004, at 18:20:55
In reply to Re: Buspar » krybrahaha, posted by Questionmark on February 25, 2004, at 0:57:03
> > > I have read previous posts that have to do with this, but I have a few questions that I couldn't find answers to. Please let me know if anyone has info on this!!!
> > >
> > > I am currently taking 300mg of Wellbutrin and 10mg of Lexapro. I do not feel depressed any more. I may experience depression for one day. My anxiety has gone down quit a bit also. However the old nasty side effect of not being able to achieve orgasim is what I am fighting currently. I am going to ask my Dr about adding Buspar. I was wondering if those of you who have used this to augment this s/e could give me some details? Any and all details would be welcomed!! How long did it take to start working? Was it a significant improvement? How else did Buspar effect you? Will it be more relaxing?
> > >
> > > I have done research on this and I have found that Buspar is suppose to take the levels of seratonine and other chemicals down. Won't this interfere with my SSRI? Isn't the point of the SSRI to up my levels of seratonine! I'm a bit confused about this.
> >
> >
> > I take 300 mgs of Luvox and noticed I couldnt have an orgasm. My P-doc put me on Buspar 10 mgs twice daily----it took about 3 weeks, but, ya it works great. My sexual level is right back to where it was.
> >
> > What SSRI's do is raise serotonin throughout your whole brain. Buspar does decrease serotonin, but the receptor it reduces it at has to do with the side effect of sexual dysfunction, so it works perfectly. This is primarily the receptor in which if it has too much serotonin can cause ssri side effects like anxiety, and sexual dysfunction.
>
> i don't believe that's true. The 5-HT2A receptor is serotonin receptor most implicated in the cause of sexual dysfunction. i think Buspar primarily only acts on 5-HT1A receptors (of the 5-HT receptors, that is). It is most likely its actions on the DA2 and alpha-2 adrenergic receptors that is responsible for its alleviation of sexual problems. i'm still really confused about the overall results of its 5-HT1A effects though-- as far as affective ANd sexual effects. i don't get it.
I dont claim to be no doctor---thats just what my psychiatrist told me. Who cares how it works as long as it works!!
Posted by Questionmark on February 26, 2004, at 1:52:29
In reply to Re: Buspar, posted by krybrahaha on February 25, 2004, at 18:20:55
> > > I take 300 mgs of Luvox and noticed I couldnt have an orgasm. My P-doc put me on Buspar 10 mgs twice daily----it took about 3 weeks, but, ya it works great. My sexual level is right back to where it was.
> > >
> > > What SSRI's do is raise serotonin throughout your whole brain. Buspar does decrease serotonin, but the receptor it reduces it at has to do with the side effect of sexual dysfunction, so it works perfectly. This is primarily the receptor in which if it has too much serotonin can cause ssri side effects like anxiety, and sexual dysfunction.
> >
> > i don't believe that's true. The 5-HT2A receptor is serotonin receptor most implicated in the cause of sexual dysfunction. i think Buspar primarily only acts on 5-HT1A receptors (of the 5-HT receptors, that is). It is most likely its actions on the DA2 and alpha-2 adrenergic receptors that is responsible for its alleviation of sexual problems. i'm still really confused about the overall results of its 5-HT1A effects though-- as far as affective ANd sexual effects. i don't get it.
>
>
> I dont claim to be no doctor---thats just what my psychiatrist told me. Who cares how it works as long as it works!!For one individual on it, maybe. But when you're sharing information with others, and the manner in which different drugs exhert their effects and interact with each other is important information (esp. for helping some decide what they want to be on/ what they should try), then there is very good reason to care about this (the precise and accurate pharmacology, etc. of specific meds). Not meaning to sound rude just meaning to make you/others aware of this.
Posted by HIBA on March 1, 2004, at 8:05:21
In reply to Re: Buspar, posted by krybrahaha on February 25, 2004, at 18:20:55
Good point. Theories are only theories. For instance, look upon the action of Tianeptine, that French molecule which used to treat depression very effectively. It is a serotonin accelerator means taking as much as serotonin out of your system. Still it works. How strange ?
I haven't had much luck with buspar, because it gave me an awesome black mood and made me extremely nauseated. But I remember it made everything more intense while I was on it. The numbing sensation of Prozac was well countered by it. But als! those side effects... If there was a medication similar to buspar without those side effects!
HIBA
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