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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by rod on July 21, 2003, at 15:04:54
Hi folks,
After having great sucess on Picamilon (just day 3 on 360 mg) i really want to stay on such a drug, but do not want to pay it on my own. I am able to get Piracetam, Pyritinol or Piroxicam on prescription, which pays my insurance :-). I haven't talked with my doc about it, but I am sure he will give the above mentioned a try, since Ritalin and Concerta did not really work and I got severly depressed for a few days after the effect stopped. Its just not worth it. Adrafinil was the worst for me.
I would really love to hear about any persomal expereinces with either Piracetam, Pyritinol or Piroxicam.
thanks
Roland
Posted by Griobhtha on July 21, 2003, at 18:58:03
In reply to Anyone tried Piracetam, Pyritinol or Piroxicam??, posted by rod on July 21, 2003, at 15:04:54
I tried Piracetam about 8 years ago after reading the first Smart Drugs book. While it is not available in the US (hence no insurance coverage), it can be purchased from overseas companies and shipped to the US using the FDA's personal use exemption.
At the time, I added it to Prozac, and it was a WONDERFUL addition. My energy level increased dramatically and it seemed to augment or work synergistically with the SSRI, so that I felt the best I had felt since before my depression kicked in. I was taking 600mg 3 times per day. It has a short half-life. I took it for approximately 6 months.
Unfortunately, even though it is relatively inexpensive (if bought in bulk), I didn't have the money to continue it. Prozac never worked as well by itself. I've thought about purchasing it again, but haven't done so.
If someone is BiPolar, I would strongly reccomend that a reliable mood stabilizer is in place before taking Piracetam.
John
Posted by rod on July 22, 2003, at 9:21:31
In reply to Re: Anyone tried Piracetam, Pyritinol or Piroxicam?? » rod, posted by Griobhtha on July 21, 2003, at 18:58:03
Hi,
Thank you for your reply!
> I tried Piracetam about 8 years ago after reading the first Smart Drugs book. While it is not available in the US (hence no insurance coverage), it can be purchased from overseas companies and shipped to the US using the FDA's personal use exemption.
>
> At the time, I added it to Prozac, and it was a WONDERFUL addition. My energy level increased dramatically and it seemed to augment or work synergistically with the SSRI, so that I felt the best I had felt since before my depression kicked in. I was taking 600mg 3 times per day. It has a short half-life. I took it for approximately 6 months.
>Sounds great!
> Unfortunately, even though it is relatively inexpensive (if bought in bulk), I didn't have the money to continue it. Prozac never worked as well by itself. I've thought about purchasing it again, but haven't done so.
>
> If someone is BiPolar, I would strongly reccomend that a reliable mood stabilizer is in place before taking Piracetam.
>
> JohnI will keep that in mind, although I am not BiPolar (at least not officially diagnosed).
Posted by rod on July 22, 2003, at 10:15:23
In reply to Anyone tried Piracetam, Pyritinol or Piroxicam??, posted by rod on July 21, 2003, at 15:04:54
It seems this drugs are not available in the US, so I'm posting some facts about, for those who are interested in it. (I will use altavistas babelfish for this and try to make some corrections by hand, so dont be surprised about bad english)
PIRACETAM:
(Nootropil)Piracetam improves higher integrative central functions such as memory -, learn -, view -, think- and concentration-ability.
Nootropil improved also the metabolism of the cells of the cerebral cortex and leads across a increased conversion of ATP, glucose and ribonucleiacid to an increase of the protein metabolism. Thus Nootropil promotes the power supply of the brain, increases the brain achievement and has a protective effect against different central damaging Noxen. These characteristics become apparent by improvement of learning and the memory and promotion of intracerebral communication.
Apart from an activation of the central energy and protein metabolism under Nootropil, also specific effects are observed on the cerebral neuro transmission. Newer investigations show that Nootropil favorably affects also the flow characteristics of the blood.
From it result:
* intensified protection of the brain in relation to hypoxia;
* Shortening of the cerebral recovery period;
* Improvement of memory and learning functions;
* Easement of the information transfer from a hemisphere to the other one as well as
* Reinforcement of cortical control of subcortical neural structures.
Thereby above all an improvement of Psychasthenie (means "confusion"), the disturbances of attention and memory, disturbed psychomotor activity and adjustment to the environment.
PYRITINOL:Pyritinol is a encephalotropic substance, whose pharmacologic main effect is the improvement of a disturbed brain metabolism. Favorable effects of the substance on the cerebralen glucose metabolism, the protein metabolism and the neural phospholipid and acetyl choline metabolism were determined.
Apart from these biochemical effects Pyritinol normalizes the blood fluidity and increases the regional brain blood circulation in lack-supplied with blood areas. Damaging influences on the nerve cells are decreased by Pyritinol. In the EEG Pyritinol leads to an activation of cortical and subcortical structures (Formatio reticularis mesencephali, Limbic system) and and thereby increases vigilance (or vigility?). Clinically the effect shows up in an improvement of disturbances of the brain function and the brain achievement in particular the symptoms memory disturbances, lack of concentration, drive poverty, depressive detuning and fatigue.
PIROXICAM:
(the primary use of this drug is e.g. arthritis, althoug is is in the same international drug classification as Piracetam and Pyritinol: ATC-Code: N06BX (Nootropics))Piroxicam is a nonseroidic Antiphlogisticum from the group of the Oxicame, whose impact is predominantly based on an inhibition of the Prostaglandinsynthesis. In addition Piroxicam restrains the cell migration of monocytes and polymorphonuclear leukocytes as well as the release of oxygen radicals from activated leukocytes. Piroxicam works antiinflammatorc, analgetic and antipyretic.
Posted by JonW on July 22, 2003, at 19:15:20
In reply to Anyone tried Piracetam, Pyritinol or Piroxicam??, posted by rod on July 21, 2003, at 15:04:54
> Hi folks,
>
> After having great sucess on Picamilon (just day 3 on 360 mg) i really want to stay on such a drug, but do not want to pay it on my own. I am able to get Piracetam, Pyritinol or Piroxicam on prescription, which pays my insurance :-). I haven't talked with my doc about it, but I am sure he will give the above mentioned a try, since Ritalin and Concerta did not really work and I got severly depressed for a few days after the effect stopped. Its just not worth it. Adrafinil was the worst for me.
>
> I would really love to hear about any persomal expereinces with either Piracetam, Pyritinol or Piroxicam.
>
> thanks
>
> RolandI have tried piracetam, but find aniracetam much smoother and gentler. Piracetam was also anxiogenic for me, where aniracetam reduces anxiety. Both were mood elevating and cleared my head, but piracetam made me irritable. Piracetam is cheap, and anyone on a nootropic should try it just to see if they couldn't save some money by switching.
Jon
Posted by rod on July 23, 2003, at 15:50:34
In reply to Re: Anyone tried Piracetam, Pyritinol or Piroxicam??, posted by JonW on July 22, 2003, at 19:15:20
> I have tried piracetam, but find aniracetam much smoother and gentler. Piracetam was also anxiogenic for me, where aniracetam reduces anxiety. Both were mood elevating and cleared my head, but piracetam made me irritable. Piracetam is cheap, and anyone on a nootropic should try it just to see if they couldn't save some money by switching.
>
> JonI did not know about aniracetam. Thank you for the info!
Roland
Posted by rod on July 25, 2003, at 10:05:40
In reply to Re: Anyone tried Piracetam, Pyritinol or Piroxicam » JonW, posted by rod on July 23, 2003, at 15:50:34
My Doc said Piracetam is nonsense and it does not work on vasodilation. Its of course doing something, but does not enhance cerebral blood flow, he said. I live in a country, where you can get Piracetam on prescription, and the insurance authority does not cover the cost anymore, because of ineffectiveness. Same for Gingko B. (EGb 761), there is also no real scientfific proof and they also stopped covering the costs.
And about Picamilone he said: "GABA? Sounds like drug abuse! Please dont do this!" The good response to Picamilone might have other reasons...
*I* trust him.
He recommended Fish Oil, as one of the things that really work on cerebral blood flow (beside some Alzheimer drugs).Roland
Posted by JonW on July 25, 2003, at 12:41:55
In reply to Opinion of my PDoc on Piracetam and Picamilone, posted by rod on July 25, 2003, at 10:05:40
> My Doc said Piracetam is nonsense and it does not work on vasodilation. Its of course doing something, but does not enhance cerebral blood flow, he said. I live in a country, where you can get Piracetam on prescription, and the insurance authority does not cover the cost anymore, because of ineffectiveness. Same for Gingko B. (EGb 761), there is also no real scientfific proof and they also stopped covering the costs.
> And about Picamilone he said: "GABA? Sounds like drug abuse! Please dont do this!" The good response to Picamilone might have other reasons...
> *I* trust him.
> He recommended Fish Oil, as one of the things that really work on cerebral blood flow (beside some Alzheimer drugs).
>
> RolandI agree that the racetams are rather mild in their effect. My impression with meds, so far at least, is you don't get real potency without side-effects. However, that's not to say these drugs have no effect. I would say aniracetam makes my head clearer, which isn't necessarily saying it makes me "smarter", and definitely reduces anxiety and boosts my mood a bit. For me, aniracetam's effects are mild but crucial. I feel the same about moclobemide (the other drug I take) and the combined effect seems somewhat synergistic. It may also be important to note that I believe CBT and philosophical disposition are just as important to overcoming my problems as are the meds. Find what works for you, and good luck! I hear persistence pays off...
Jon
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