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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Peter S. on March 3, 2003, at 13:41:54
Anyone had experience combining SSRIs? I've heard one positive report with Prozac and Lexapro. I'm wary though of serotonin syndrome.
Thanks.
Peter S.
Posted by KrissyP on March 3, 2003, at 23:13:09
In reply to Combining SSRIs?, posted by Peter S. on March 3, 2003, at 13:41:54
Hi,
I personally have not ever been on 2 SSRI's BUT, my sibling has been on Wellbutrin AND Zoloft-it didn't help. Now is only on Zoloft and seems to be doing pretty good. Sorry I can't be of more help to you, but I hope this helped a little?
Kristen
-------------------------------------------------Anyone had experience combining SSRIs? I've heard one positive report with Prozac and Lexapro. I'm wary though of serotonin syndrome.
Thanks.
Peter S.
Posted by ace on March 4, 2003, at 0:43:06
In reply to Combining SSRIs?, posted by Peter S. on March 3, 2003, at 13:41:54
> Anyone had experience combining SSRIs? I've heard one positive report with Prozac and Lexapro. I'm wary though of serotonin syndrome.
>
> Thanks.
>
> Peter S.I simply wouldn't do it -- even at low dose. The chance of hyperprexic crisis (serotonin syndrome) is just too high. How about Prozac with a TCA, or atypical antipsychotic. That works well for a whole range of probs.
Be Safe,
Ace.
Posted by Peter S. on March 4, 2003, at 20:10:12
In reply to Re: Combining SSRIs? » Peter S., posted by ace on March 4, 2003, at 0:43:06
Hi Ace,
I've been looking for examples where combining SSRIs caused serotoninergic syndrome and haven't found any. The literature mostly is concerned with combining MAOIs with SSRIs or other drugs. Based on this it's hard to tell how risky it is. My pdoc thinks it's low risk as long as I take it slow. At this point for me the possibility of any kind of payoff is worth the risk.
> > Anyone had experience combining SSRIs? I've heard one positive report with Prozac and Lexapro. I'm wary though of serotonin syndrome.
> >
> > Thanks.
> >
> > Peter S.
>
> I simply wouldn't do it -- even at low dose. The chance of hyperprexic crisis (serotonin syndrome) is just too high. How about Prozac with a TCA, or atypical antipsychotic. That works well for a whole range of probs.
>
> Be Safe,
> Ace.
Posted by ace on March 5, 2003, at 3:12:41
In reply to Re: Combining SSRIs?-Ace, posted by Peter S. on March 4, 2003, at 20:10:12
> Hi Ace,
>
> I've been looking for examples where combining SSRIs caused serotoninergic syndrome and haven't found any. The literature mostly is concerned with combining MAOIs with SSRIs or other drugs. Based on this it's hard to tell how risky it is. My pdoc thinks it's low risk as long as I take it slow. At this point for me the possibility of any kind of payoff is worth the risk.
>
>
>
>
> > > Anyone had experience combining SSRIs? I've heard one positive report with Prozac and Lexapro. I'm wary though of serotonin syndrome.
> > >
> > > Thanks.
> > >
> > > Peter S.
> >
> > I simply wouldn't do it -- even at low dose. The chance of hyperprexic crisis (serotonin syndrome) is just too high. How about Prozac with a TCA, or atypical antipsychotic. That works well for a whole range of probs.
> >
> > Be Safe,
> > Ace.
>
>
I still don't recomend it. In my literature it is a big no-no. But of you doc thinks it's fine
I'd give it a try. BUT PLEASE BE VERY VERY CAREFUL. have the syptoms of serotonin syndrome always with you to make sure. Still...I think an antipsychotic would be best.Ace.
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