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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by sarahk0 on January 27, 2003, at 19:04:14
A few months ago my pdoc told me he'd like to put me on reboxetine when it became available in the US. I had heard of it, and started my search for when it would be here. My fellow Americans, here's what Pharmacia told me:
Your e-mail request for information regarding VESTRA (reboxetine mesylate tablets) was forwarded to Pharmacia’s Medical & Drug Information Unit. Pharmacia Corporation is no longer seeking FDA approval for VESTRA Tablets in the U.S. for the treatment of depression.
Thank you for your interest in VESTRA.
Sincerely,
Medical & Drug Information
Pharmacia Corporation
I guess next appointment I will be letting him know he needs to start looking elsewhere for hope. Things don't look so good here. He's run out of ideas. Suppose that means it falls to me.Take Care!
Posted by noa on January 27, 2003, at 20:16:00
In reply to Vestra (reboxetine mesylate) U.S., posted by sarahk0 on January 27, 2003, at 19:04:14
Oh well--that is too bad. I know that reboxetine has been discussed for a long time here at PB.
BTW, and fwiw, my pdoc told me that Straterra (atomoxatine) is somewhat similar to Reboxetine. I don't know the details, though. He said he has worked with one patient who buys the reboxetine from England.
Posted by falconman on January 27, 2003, at 20:33:32
In reply to Re: Vestra (reboxetine mesylate) U.S., posted by noa on January 27, 2003, at 20:16:00
I've been on a course of reboxetine and it effected me particularly badly. Being strictly a noradrenaline re-uptake inhibitor makes this drug fairly novel, and could be a potent antidepressant especially for people who have a profound lack in drive and energy. Its a shame its not available in the US as it is in England and I'm sure this must be frustrating for you. If its any concellation, within 5 days of being on its initial starting dose, I was having uncharacteristic angry outbursts and I felt more suicidal then ever before. Maybe it shouldn't be available, although I understand that my reaction to it was fairly atypical.
regards
Posted by BekkaH on January 27, 2003, at 22:29:37
In reply to Vestra (reboxetine mesylate) U.S., posted by sarahk0 on January 27, 2003, at 19:04:14
Sarah, you might want to discuss Strattera (atomoxetine) with your doctor. Like reboxetine, it is a selective norepinephrine reuptake inhibitor. Unlike reboxetine, Strattera IS available in the U.S. It is an antidepressant that is currently being marketed as a drug for treatment of ADD/ADHD. It just became available this month (January 2003). If you look through some of the posts above and in the archives for the past two weeks, you will find some PB members' comments on it. If your doctor wants to research it, as I mentioned, the generic name is atomoxetine. The generic name was originally tomoxetine, but it was changed to atomoxetine because tomoxetine sounded too much like another drug. Lilly, the company that makes the drug, has a website for it, at www.strattera.com.
Posted by JohnL on January 28, 2003, at 6:08:58
In reply to Vestra (reboxetine mesylate) U.S., posted by sarahk0 on January 27, 2003, at 19:04:14
If you want Reboxetine, it is very easily available on the web from overseas. But quite honestly, there have been a lot of people here over the years that have tried it, and I can't remember even one person who liked it longterm. Side effects can be harsher than indicated in literature. I tried it myself and it was awful. It caused an immediate profound worsening of my depression, and side effects were nasty.
The reason they aren't going for FDA approval any more is because the preliminary trials did not pan out as good as expected. Of course, anyone watching this board over the years would have already been able to predict that.
If you want an antidepressant with norepinephrine action, then Desipramine or Nortriptyline would be good choices. Effexor too.
I have no idea what your symptoms are, but don't forget the antipsychotics such as Zyprexa. They are proving extremely helpful with tough to treat psychiatric cases of all sorts, especially when combined with antidepressants. When they named them "antipsychotics", they made a big mistake, because they do a whole lot more than that. I even saw one clinical research study that claimed antipsychotics are antidepressants.
John
Posted by Phil on January 28, 2003, at 7:02:59
In reply to Re: Vestra (reboxetine mesylate) U.S., posted by JohnL on January 28, 2003, at 6:08:58
I agree w/ John. I was incredibly hopeful about Reboxetine and with my pdocs blessing, tried it a few years ago. Probably the most disappointing drug I've ever taken. Like John, I don't remember anyone who had good luck with it.
It does sound promising on paper but I was off of it in days.
This is the end of the thread.
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