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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Dave1 on December 26, 2002, at 9:01:41
HI,
Has anyone had success augmenting an antidepressant with something else when the antidepressant alone didn't work.
Dave
Posted by Etherealightning194 on December 26, 2002, at 9:11:00
In reply to augmentation, posted by Dave1 on December 26, 2002, at 9:01:41
Hi, yes my last pdoc, an italian luminary called Cassano put me on Mirapexin in addition to celexa, even if I was feeling quite speedy it was good enough for motivation.Mirapexin is a dopamine agonist used either for parkinsons or for antidepressant augmentation.It holds some interesting neuroperotective qualities, like upregulation of antioxidant enzimes,give it a try.
L.
Posted by ubergenius on December 26, 2002, at 9:34:32
In reply to Re: augmentation, posted by Etherealightning194 on December 26, 2002, at 9:11:00
There are many methods to augment an antidepressant that is only partially working. It seems that my doc adds another antidepressant or sometimes even an antipsychotic or major tranquilizer. I really think it depends on which symptoms of the depression the first antidepressant did not fix, as to what augmenting drug the doc will prescribe.
UG
Posted by Dave1 on December 26, 2002, at 20:16:37
In reply to Re: augmentation, posted by Etherealightning194 on December 26, 2002, at 9:11:00
Most of the doctors I see are idiots. They don't know how, or don't want to give anything except one basic antidepressant with nothing else.
I did try clomipramine with LI which worked partially for about a week. I was really surprised that a med. could actually help me.
Last session I brought up thyroid hormone and the doc said maybe we could try that with a TCA.
It seems like augmentation has mainly been documented with the TCAs. Anything with an SSRI is undocumented, although I did see some research on adding a drug could PINDOLOL to an SSRI. For some reason I think it will work. But, the doc says no. I've also tried SSRI + neuroepileptic which failed.
I did add remeron to effexor, but not long enough. I also add wellbutrin to something but again not long enough.
I have to look into that drug in the first post. I'm not familiar with it.
Thanks,
Dave
Posted by cybercafe on December 27, 2002, at 2:15:28
In reply to Re: augmentation, posted by Dave1 on December 26, 2002, at 20:16:37
i believe pindolol augmentation is to make it work faster, not betterother standard methods like lithium augmentation
and T3/T4 augmentation have been questioned (though i'd give them a try)...
compared to just continuing to raise your dose
(lithium is thought to add to serotonin reuptake effects)adding a stimulant sounds like a good idea, though
i worry about tolerance (i have zero knowledge on this matter)adding an antipsychotic sounds like a good idea for
mixed states, though i would stay low dose low potency and only as a last resort
(zyprexa has been good to me)of course i'm assuming you've tried an MAOI
> Most of the doctors I see are idiots. They don't know how, or don't want to give anything except one basic antidepressant with nothing else.
>
> I did try clomipramine with LI which worked partially for about a week. I was really surprised that a med. could actually help me.
>
> Last session I brought up thyroid hormone and the doc said maybe we could try that with a TCA.
>
> It seems like augmentation has mainly been documented with the TCAs. Anything with an SSRI is undocumented, although I did see some research on adding a drug could PINDOLOL to an SSRI. For some reason I think it will work. But, the doc says no. I've also tried SSRI + neuroepileptic which failed.
>
> I did add remeron to effexor, but not long enough. I also add wellbutrin to something but again not long enough.
>
> I have to look into that drug in the first post. I'm not familiar with it.
>
> Thanks,
>
> Dave
>
Posted by jimmygold70 on December 27, 2002, at 7:24:21
In reply to augmentation, posted by Dave1 on December 26, 2002, at 9:01:41
There are dosens of ways to augment - add another AD with a different mechanism, Lamictal, Lithium.
Posted by Dave1 on December 27, 2002, at 14:48:45
In reply to Re: augmentation » Dave1, posted by jimmygold70 on December 27, 2002, at 7:24:21
HI,
Thanks for all the follow up.
I just went to my pdoc this morning. He gave me effexor + lithium + thyroid hormone. Maybe it'll work. He said he didn't think much of pindolol.
Also there's research on thyroid hormone that says it helps ECT work better and I was considering ECT.
Dave
This is the end of the thread.
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