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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by wingedcat on December 22, 2002, at 20:12:14
I ask because a close compound, Modafinil, interacts with steroid contraceptives (oral, injection, and implants).
Modafinil and contraceptives are both metabolized by the liver enzyme CYP3A4, according to provigil.com.
I couldn't find if Adrafinil interacts with them, which is strange considering Adrafinil has been around longer.
Thanks!
Posted by Larry Hoover on December 23, 2002, at 9:23:27
In reply to Does adrafinil interact with birth control pill?, posted by wingedcat on December 22, 2002, at 20:12:14
> I ask because a close compound, Modafinil, interacts with steroid contraceptives (oral, injection, and implants).
>
> Modafinil and contraceptives are both metabolized by the liver enzyme CYP3A4, according to provigil.com.Modafinil induces 3A4, which would have the effect of reducing the potency of the birth control pill.
> I couldn't find if Adrafinil interacts with them, which is strange considering Adrafinil has been around longer.
>
> Thanks!I can't find anything on adrafinil either.
Posted by medlib on December 29, 2002, at 20:32:23
In reply to Re: Does adrafinil interact with birth control pill?, posted by Larry Hoover on December 23, 2002, at 9:23:27
Hi wingedcat--
The primary metabolite of adrafinil is modafinil. Also, there are isolated reports from clinical studies that adrafinil increased sexual interest. Sounds like a backup method of contraception is called for.
medlib
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