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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by Minx on November 11, 2002, at 15:34:32
I am currently taking Parnate (MAOI) for atypical depression, and Mellaril to help my BPD. I have been on Parnate several times, and each time, I build up tolerance, until my doctors will not increase my dosage, and I have to be taken off of it for a year or so until my system clears out. This then puts me on the "pill of the month club" (as my friends and I so lovingly put it) - that wonderful merry-go-round of try this, try that wait two weeks, wait a month, try this again, try that other one...all the while living in hell because I don't respond to ANY SSRI's, nor Wellbutrin, and Effexor makes me too sick to even try.
I have heard about a new medication (antipschotic?) called Geodon; somebody told me that it has shown some promise with treatment resistant depression. Don't know if that's true...But it would be nice to just have to take one med instead of two (and I really miss my cheese & beef jerky). Has anybody here heard about it?
Any other suggestions for atypical, treatment-resistant depression? I like to be informed - it helps me and my doctor, and I can be a little more prepared for what could be coming down the road...
Posted by jsarirose on November 14, 2002, at 16:31:13
In reply to Increasing MAOI tolerance - What are my options?, posted by Minx on November 11, 2002, at 15:34:32
> I am currently taking Parnate (MAOI) for atypical depression, and Mellaril to help my BPD. I have been on Parnate several times, and each time, I build up tolerance, until my doctors will not increase my dosage, and I have to be taken off of it for a year or so until my system clears out. This then puts me on the "pill of the month club" (as my friends and I so lovingly put it) - that wonderful merry-go-round of try this, try that wait two weeks, wait a month, try this again, try that other one...all the while living in hell because I don't respond to ANY SSRI's, nor Wellbutrin, and Effexor makes me too sick to even try.
> I have heard about a new medication (antipschotic?) called Geodon; somebody told me that it has shown some promise with treatment resistant depression. Don't know if that's true...But it would be nice to just have to take one med instead of two (and I really miss my cheese & beef jerky). Has anybody here heard about it?
> Any other suggestions for atypical, treatment-resistant depression? I like to be informed - it helps me and my doctor, and I can be a little more prepared for what could be coming down the road...Have you tried augmenting the Parnate when it starts petering out? There are several meds that work well with Parnate. Also, how high of dose have you taken? From my research and talking with my doctor you can go up to 160mg as long as your blood pressure doesn't drop too much and you're not too dizzy. If you can handle the side effects though you may want to bump it higher. I was up to 100mg before I was too dizzy. I split the dose into three, four, and three pills every three hours. Also, Lithium is a common augmenting drug, or Lamictal (which I'm currently tapering up on). There are many others as well.
I have had treatment resistant depression for years as well. Since Parnate is the first thing in years to work I would be very hesitant to go off for a year.
Good luck,
Jessica
This is the end of the thread.
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