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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by LostBoyinNC1 on September 1, 2002, at 17:28:08
Ive been doing some research comparing the qualities of Lexapro to the selegiline MAOI patch. Ive come to the following conclusions based upon my research:
1) Lexapro is mainly a serotonin drug. It increases serotonin, but thats all. Its basically a new and improved Celexa, which is an SSRI.
2) The Selegiline MAOI patch works totally different than Lexapro. It increases levels of all major neurotransmitters in the brain, not just serotonin. The MAOI patch increases all of the monoamines in the brain to include both MAO-B and MAO-A which includes the the following. serotonin, dopamine, norephinephrine, PEA, various trace amines SSRIs dont even touch. The selegiline MAOI patch can also treat parkinsons, thus it wouldnt be likely to cause akathisia like Lexapro would.
Additionally the Selegiline MAOI patch lowers blood pressure, an added side effect which would benefit many people.
Lexapro was approved by the FDA recently. The Selegiline MAOI patch, developed by Somerset pharmaceuticals for both depression and parkinsons, was shot down by the FDA this past March. Why is that?
As a direct result of my research, Ive come to the following very specific and clear conclusion. The MAOI patch is a vastly superior antidepressant, especially for severe depression. It could also greatly benefit depressives who have hypertension.
Hmmmmmmmmmm golly gee, whats going on here? Why do we need more "me too" serotonin SSRI antidepressants? How many SSRIs will we have in another 10 years? Fifteen different SSRIs?
LostBoyinNC
Posted by jsarirose on September 1, 2002, at 21:36:18
In reply to Lexapro versus the MAOI patch, posted by LostBoyinNC1 on September 1, 2002, at 17:28:08
I've heard you don't have to follow the diet restrictions of regular MAOIs with the patch. As Parnate has been one of only two drugs to ever help me (15 years of trying) I would very much like to see it approved. Of course I don't want something that isn't safe. I haven't heard anything about why it wasn't approved. I'd be curious to know why too.
-Jessica (no fool, I know the FDA is political just like every other branch of the government)
This is the end of the thread.
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