Psycho-Babble Medication Thread 116915

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What's an antagonist and what does it do?

Posted by denise528 on August 19, 2002, at 6:17:39

Hello,

Anyone out there know what an antagonist (I'm sure somebody does) is and what it does?

Denise

Re: What's an antagonist and what does it do? » denise528

Posted by IsoM on August 19, 2002, at 12:46:56

In reply to What's an antagonist and what does it do?, posted by denise528 on August 19, 2002, at 6:17:39

You'll often find the term 'antagonist' used along with 'synergist'. An antagonist is any compound or drug that counteracts or neutralizes the effects of another compound (whether medication, vitamin or mineral, or natural body substance). A synergist is a drug or compound that increases the action of another medication, vitamin or mineral, or natural body compound.

Example of a antagonist is tannins in conjunction with iron. Tannins interfere with the absorption of iron from foods. Example of a synergist is vitamin C with iron. It increases the absoprtion.

Mind you, the matter of absorption is not the only action of antagonists & synergists but only one example.

Re: What's an antagonist and what does it do?

Posted by OddipusRex on August 19, 2002, at 13:26:25

In reply to What's an antagonist and what does it do?, posted by denise528 on August 19, 2002, at 6:17:39

Naturally occuring neurotransmitters are agonists which stimulate receptors. Antagonists are drugs which block the agonist at its receptor. Antagonists have no action of their own in the absence of agonists.

> Hello,
>
> Anyone out there know what an antagonist (I'm sure somebody does) is and what it does?
>
> Denise

Re: Thanks to both of you for the explanations(nm)

Posted by denise528 on August 20, 2002, at 4:42:10

In reply to Re: What's an antagonist and what does it do?, posted by OddipusRex on August 19, 2002, at 13:26:25

.

Re: Thanks to both of you for the explanations

Posted by denise528 on August 20, 2002, at 12:00:45

In reply to Re: Thanks to both of you for the explanations(nm), posted by denise528 on August 20, 2002, at 4:42:10

Hi,

Sorry another question, so what would a 5HT2c agonist do? A previous thread read that the following new medications are in the pipeline but I don't understand what they do.

Organon has the following in its pipeline:
5ht1a agonist (ariza) phase 3
5ht2c agonist
dopamine + serotonin + norepinephrine reuptake inhibitor
GRF antagonist

Thanks for any advice.....Denise

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