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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by DsevenO on June 25, 2002, at 17:53:00
I am currently taking 100mg of Zoloft, with limited success. It helps with my physical pain and my depressive/anxiety symtoms. I am always very, very tired and I have hypersomnia (10-12 hours sleep/day). The depression is still a big problem, but taking anything more than 100 mg of Zoloft causes heart palpitations, and at less than 100 mg I have a worsening of my original symptoms.
I tried Prozac a little while ago, and at first I loved it; I was finally getting back the energy and enthusiasm I once had (I used to be borderline-hyperactive; now I barely move). The problem was, I couln't take more than 10mg of Prozac without becoming very anxious, even panicked. And 10mg wasn't enough because I suffer from so many somatic symptoms.
So here is my quandry: a tolerable dose of each on its own is not enough, so could I combine a low dose of each to get the energizing/mood enhancing qualities of Prozac (say 5-10mg) and the anxiolyitic/pain relieving qualites of Zoloft (say 50mg)?
Any thoughts, suggestions, warnings would be appreciated.
Posted by katekite on June 27, 2002, at 20:01:45
In reply to Taking Prozac with Zoloft?, posted by DsevenO on June 25, 2002, at 17:53:00
Yes you could do that. You risk serotonin syndrome if you have too much of too many serotonin enhancing drugs around so you would have to be careful but its usually only seen with high doses.
Some people have increased anxiety for a couple weeks while starting ssris and then have that go away completely to be replaced by a pleasant activating feeling.
Perhaps you could use zoloft as a bridge to help you get onto a low dose of prozac (which would be more activating), then after a few weeks if the anxiousness goes away you could reduce the zoloft and increase the prozac.
Celexa is said to be inbetween zoloft and prozac in activation. So that would be another option.
Other activating non-ssri drugs (which can all cause anxiety in themselves) are wellbutrin and desipramine and the true stimulants like ritalin. I feel like I've forgotten something....
hope that helps.
kate
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