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Dr. Bob is Robert Hsiung, MD,
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Posted by Raga on January 10, 2002, at 8:10:30
Hi,
I am wondering if it is okay to take desipramine and buproprion (Wellbutrin) together?
I understand that desipramine is often added to SSRIs, but I haven't heard of it being added to Wellbutrin.
Has anyone done this?
-Raga
Posted by CalvaryHill on January 10, 2002, at 9:46:29
In reply to Desipramine and Wellbutrin together?, posted by Raga on January 10, 2002, at 8:10:30
That is a safe combination in which norepinephrine is boosted twice, and dopamine is boosted once. That combination may be efficacious in many affective disorders.
Posted by Raga on January 10, 2002, at 19:07:26
In reply to Re: Desipramine and Wellbutrin together? » Raga, posted by CalvaryHill on January 10, 2002, at 9:46:29
Thanks. I think my psychiatrist is going to prescribe low dose desipramine with wellbutrin 300 mg. The wellbutrin is working somewhat for my ADD, but I need a higher dose, which isn't possible due to a little tachycardia and tics...
I was actually more concerned about possible increased side effects due to the combination. I'm not too worried about too much NE or something...
Posted by CalvaryHill on January 10, 2002, at 20:21:11
In reply to Re: Desipramine and Wellbutrin together?, posted by Raga on January 10, 2002, at 19:07:26
Desipramine has a reputation for being the most benign (side-effect-wise) of the tricyclics. Its probably better than an SSRI in lack of side-effects. I'm hopeful about the combination for you.
This is the end of the thread.
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