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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by AndrewB on June 26, 2001, at 1:37:18
In reply to Re: non-prescription sources!AndrewB, posted by CraigF on June 25, 2001, at 19:29:58
Adrafinil sometimes is a good mix with amisulpride, providing energy, alertness, and motivation. In general an arousal agent of some kind, depending on what you respond to goes well with amisulpride.
Adrafinil is only available overseas.
Dosage is 150mg/day to 600 on up. Start low.
AndrewB
Posted by CraigF on June 26, 2001, at 6:57:47
In reply to Re: adrafinil-CraigF, posted by AndrewB on June 26, 2001, at 1:37:18
Thanks!
Any contraindications you are aware of? I'm still on Celexa 20 mgs with my Amisulpride
Posted by AndrewB on June 26, 2001, at 10:15:55
In reply to Re: adrafinil-CraigF » AndrewB, posted by CraigF on June 26, 2001, at 6:57:47
Craig,
Adrafinil doesn't have much published about it on drug-to-drug interactions. Others have taken it with SSRIs without incident. I think CarolAnn used it with Celexa without out incident but you might want to give a shout out to her to be safe. Of course start low (75mgs/day) and go slow.
Not recommended for those with liver impairment. Liver function should have been checked before one uses it and periodically afterwards if use is continued.
One report on this board of a hypertensive crisis between Adrafinil and an MAOI.
No problem between adrafinil and amisulpride.
Hope this helps and good luck,
AndrewB
Posted by CraigF on June 27, 2001, at 8:15:41
In reply to Re: adrafinil-CraigF, posted by AndrewB on June 26, 2001, at 10:15:55
Thanks again...
And I'll be able to contribute to your Amisulpride study pretty soon. I've been at 50 mgs. for three weeks, but I'm still pulling the Celexa out of the mix. I'll know more in a couple of weeks.
Posted by Sunny on June 27, 2001, at 11:38:26
In reply to Re: Amisulpride study » AndrewB, posted by CraigF on June 27, 2001, at 8:15:41
I'm wondering about any adverse reactions between adrafinil & serzone. Has anyone tried the combo?
I'm hoping the adrafinil will help with serzone sedation.
Thanks,
Sunny> Thanks again...
>
> And I'll be able to contribute to your Amisulpride study pretty soon. I've been at 50 mgs. for three weeks, but I'm still pulling the Celexa out of the mix. I'll know more in a couple of weeks.
Posted by Rick on June 30, 2001, at 0:58:32
In reply to Re: Amisulpride study, posted by Sunny on June 27, 2001, at 11:38:26
FWIW, I've been taking Serzone -- all in the daytime -- with 100 mg of modafinil, and they really seem to go together well. As you probably know, modafinil (brand Provigil/Alertec in U.S./Canada) is the primary metabolite of adrafinil and thought to provide most of the theraputic value. The combo really seems to balance out side effects (e.g., P fights S sedation and S keeps any P agitation at bay), while the *theraputic* effects are nicely synergystic.
I added the Provigil initially to counter Serzone fatigue, but the combo clicked so well (as long as I don't exceed 100mg Provigil too often) that I stayed with it. There are possible interactions between the two meds mediated by the CYP450 enzyme system, so monitoring is advisable. (Heck, monitoring advisable if you're taking just about *anything* with Serzone, including non-psychotropics.) ESPECIALLY with adrafinil -- which requires quarterly liver function tests -- you'd better be cautious. (I'm not sure how adrafinil is metabolized.)
Rick
> I'm wondering about any adverse reactions between adrafinil & serzone. Has anyone tried the combo?
> I'm hoping the adrafinil will help with serzone sedation.
> Thanks,
> Sunny
>
> > Thanks again...
> >
> > And I'll be able to contribute to your Amisulpride study pretty soon. I've been at 50 mgs. for three weeks, but I'm still pulling the Celexa out of the mix. I'll know more in a couple of weeks.
This is the end of the thread.
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