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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by dennis on January 9, 2001, at 23:26:24
I just thought I would let you people know that I have been taking amisulpride for a little over a month and I just started taking adrafinil 2 days ogo, the amisulpride has definitly helped and I can feel the adrafinil working already, I am in much better shape now than I was. I can remember 2 months ago I was deep in depression with no desire to do anything and had no hope for the future, I want to thank JohnL, you contribute to this forum a lot and you helped me decide to try these drugs. While I am talking I might as well say I'm sorry if I made anybody mad with my earlier post where I tried to sell herbal products.
Posted by JohnL on January 10, 2001, at 6:29:48
In reply to just thought id let you know, posted by dennis on January 9, 2001, at 23:26:24
> I just thought I would let you people know that I have been taking amisulpride for a little over a month and I just started taking adrafinil 2 days ogo, the amisulpride has definitly helped and I can feel the adrafinil working already, I am in much better shape now than I was. I can remember 2 months ago I was deep in depression with no desire to do anything and had no hope for the future, I want to thank JohnL, you contribute to this forum a lot and you helped me decide to try these drugs. While I am talking I might as well say I'm sorry if I made anybody mad with my earlier post where I tried to sell herbal products.
Dennis,
I'm so glad to hear Amisulpride and Adrafinil are improving your life. That is awesome news!Sometimes I feel weird about it because I have to mailorder drugs from overseas to fix me? I mean, the USA has tons of drugs. Why is it that these wonder drugs exist in other countries but not here? And talk about side effects. Have you ever taken drugs that had lesser side effects than Amisulpride or Adrafanil? Not me, that's for sure.
I remember a couple months ago speaking with you and suggesting these drugs, while at the same time feeling apprehensive about getting someone else involved in self-directed care. I always feel a bit hesitant when I suggest these drugs to someone else. Though I shouldn't. They are truly marvelous drugs, far superior to anything the FDA gives us. But it always makes me a little uneasy. I didn't actually expect you would go through with it. I'm glad you did. Did you know, the first time I ordered these drugs, my wife made me flush them down the toilet? She couldn't fathom the idea of self-directed care. After a year of more drug failures prescribed by various doctors, I reordered the meds again, secretly. Now of course there is such a dramatic change in my life she would throw a fit if I even thought about stopping these meds.
Anyway, nice to hear someone else is doing well on the exact same drugs that worked wonders for me. The fact that Amisulpride has helped in less than 4 weeks, and Adrafinil is noticeable in 2 days, is impressive.
John
Posted by SLS on January 10, 2001, at 21:30:54
In reply to Re: just thought id let you know - awesome drugs!, posted by JohnL on January 10, 2001, at 6:29:48
> > I just thought I would let you people know that I have been taking amisulpride for a little over a month and I just started taking adrafinil 2 days ogo, the amisulpride has definitly helped and I can feel the adrafinil working already, I am in much better shape now than I was. I can remember 2 months ago I was deep in depression with no desire to do anything and had no hope for the future,
> I want to thank JohnL,
Me too. Believe it or not!
> you contribute to this forum a lot
Agreed.
John, I particularly like your term "self-directed care". In my mind, it better establishes the focus of responsibility. For some reason, it also conveys to me a directive to take the time to make responsible choices. If my new doctor strikes-out, and I doubt he will, I will probably feel compelled to once again take such a path.
Thank you.
Sincerely,
Scott
P.S. John, when you have the time, go back 1.5 years in the PB archives and check out some of your posts. Truly great stuff. Well-directed.
Posted by Lee on January 13, 2001, at 17:12:51
In reply to just thought id let you know, posted by dennis on January 9, 2001, at 23:26:24
> I just thought I would let you people know that I have been taking amisulpride for a little over a month and I just started taking adrafinil 2 days ogo, the amisulpride has definitly helped and I can feel the adrafinil working already, I am in much better shape now than I was. I can remember 2 months ago I was deep in depression with no desire to do anything and had no hope for the future, I want to thank JohnL, you contribute to this forum a lot and you helped me decide to try these drugs. While I am talking I might as well say I'm sorry if I made anybody mad with my earlier post where I tried to sell herbal products.
Dennis and JohnL,
How wonderful to read about your positive response to the adrafinil/amisulpride combo.
Since reading JohnL's original post on this subject I have been reading up on the two drugs. All I've read suggests I might benefit from a trial.
Did either of you discontinue antidepressant therapy before trialing these specific drugs? Or did you lower your medication while introducing adrafinil/amisulpride?
Currently I am taking Effexor XR 225 mg. and Provigil 400 mg. and have achieved light to moderate relief. (Less fatigue, depression softer). I am concerned that I may fall back into a deep depression before ad/am takes effect (if it does.) Any thoughts/suggestions would be appreciated.
Posted by dennis on January 14, 2001, at 2:41:49
In reply to Re: just thought id let you know, posted by Lee on January 13, 2001, at 17:12:51
> Did either of you discontinue antidepressant therapy before trialing these specific drugs? Or did you lower your medication while introducing adrafinil/amisulpride?I had not taken any antidepressants for 2 years before I tried reboxetine for about a week, and then right after that I went on the amisulpride. My theory was try something completely different each time, first it was prozac(seritonin), then reboxetine(noradrenaline), then amisulpride(dopamine), third times a charm.
>
> Currently I am taking Effexor XR 225 mg. and Provigil 400 mg. and have achieved light to moderate relief. (Less fatigue, depression softer). I am concerned that I may fall back into a deep depression before ad/am takes effect (if it does.) Any thoughts/suggestions would be appreciated.The way amisulpride worked was like this, the first few days there was periods of improved mood, then it slowly faded away, and I suck back down into depression a little bit, then at about week 2 I believe my mood started to slowly improve again, this slow steady improvment has continued since then and I think it is now starting to level off at the 5-6 week mark, I think I might still see some slight improvement with more time but it will probebly be very slight if any, so that might give you something to go by if you decide to try amisulpride, as for the adrafinil, it seems to be taking the same path as the amisulpride did, I could feel the adrafinil the first few days and now it has faded away a bit, I will have to wait and see on that but I am hopefull it will again show its positive effects with time. I am not sure if you are a man or woman but I have read women have side effects with amisulpride, but if your a man you will not have any problems at all. One thing that I still get is anxiety, I still occasionaly have periods of extreme anxiety to the point were I feel sick to my stomach. I am not trying to say these drugs cause anxiety, I am only trying to say these drugs dont help ease anxiety, at least not my anxiety, but still, they do a good job elevating my mood to the point where I am no longer depressed. You have to order these drugs from europe and your insurance is not going to cover them so you will be paying more money than normal for medication, you will be the doctor and patient, prescribing yourself drugs not approved by the FDA, not to say there is anything wrong with that, its just not a ordinary thing, but do you remember the story about the man who took the road less traveled, I dont, but I remember that taking that road was a good thing, maybe you can refresh my memory about that story. Regarding your current medications I dont know if you should stop them completely before going on ami/adr or not, but my gut feeling on it is you should completely stop all other drugs before starting ami/adr. You may have to wean off the effexor slowly(again I am just guessing)to avoid bad effects, the only reason why I say take take ami/adr alone is because when I first started taking amisulpride I had the bright idea of taking 0.5mg reboxetine with it, just for a small stimulant effect, even at that small dosage the reboxetine totally wiped out all good effects I was having with amisulpride, then a couple days after the rebox was out of my system I started to improve again, so there is just no telling how effexor will combine with amisulpride so again, I think if at all possible, it would be best to take ami/adr alone. That is all I can think of to tell you right now. I hope this is helpful to you.
Posted by Lee on January 14, 2001, at 16:42:19
In reply to Re: just thought id let you know, posted by dennis on January 14, 2001, at 2:41:49
> I had not taken any antidepressants for 2 years before I tried reboxetine for about a week, and then right after that I went on the amisulpride. My theory was try something completely different each time, first it was prozac(seritonin), then reboxetine(noradrenaline), then amisulpride(dopamine), third times a charm.
> > >
> The way amisulpride worked was like this, the first few days there was periods of improved mood, then it slowly faded away, and I suck back down into depression a little bit, then at about week 2 I believe my mood started to slowly improve again, this slow steady improvment has continued since then and I think it is now starting to level off at the 5-6 week mark, I think I might still see some slight improvement with more time but it will probebly be very slight if any, so that might give you something to go by if you decide to try amisulpride, as for the adrafinil, it seems to be taking the same path as the amisulpride did, I could feel the adrafinil the first few days and now it has faded away a bit, I will have to wait and see on that but I am hopefull it will again show its positive effects with time. I am not sure if you are a man or woman but I have read women have side effects with amisulpride, but if your a man you will not have any problems at all. One thing that I still get is anxiety, I still occasionaly have periods of extreme anxiety to the point were I feel sick to my stomach. I am not trying to say these drugs cause anxiety, I am only trying to say these drugs dont help ease anxiety, at least not my anxiety, but still, they do a good job elevating my mood to the point where I am no longer depressed. You have to order these drugs from europe and your insurance is not going to cover them so you will be paying more money than normal for medication, you will be the doctor and patient, prescribing yourself drugs not approved by the FDA, not to say there is anything wrong with that, its just not a ordinary thing, but do you remember the story about the man who took the road less traveled, I dont, but I remember that taking that road was a good thing, maybe you can refresh my memory about that story. Regarding your current medications I dont know if you should stop them completely before going on ami/adr or not, but my gut feeling on it is you should completely stop all other drugs before starting ami/adr. You may have to wean off the effexor slowly(again I am just guessing)to avoid bad effects, the only reason why I say take take ami/adr alone is because when I first started taking amisulpride I had the bright idea of taking 0.5mg reboxetine with it, just for a small stimulant effect, even at that small dosage the reboxetine totally wiped out all good effects I was having with amisulpride, then a couple days after the rebox was out of my system I started to improve again, so there is just no telling how effexor will combine with amisulpride so again, I think if at all possible, it would be best to take ami/adr alone. That is all I can think of to tell you right now. I hope this is helpful to you.Dennis,
Thank you for the time and attention you gave to my question. Although I know that everyone's experience with a drug is different, it does help to hear personal accounts. (Un-shared depression can be lonely.)
You mentioned possible side effects for women - I am one -so I'll continue reading up on amisulpride.
I too have anxiety disorder. Have you tried valerian? Or kava-kava? They are herbs. For me valerian helps take the edge off low-level anxiety. Although it is powerless against a full-blown anxiety attack.
I hope you'll keep us posted on how the amisulpride/adrafinil combo is working for you.
This is the end of the thread.
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