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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by SLS on July 23, 2004, at 19:07:19
Hi Racer.
About 20 years ago, a doctor I was seeing suggested that I try Periactin. It was something that seemed bizarre at the time, and has not been suggested by anyone since. If you are still willing to share your story, you can e-mail me at:
slsfan1776 at yahoo dot com
My interests most recently were in drugs that stimulate the histamine H1 receptor. Periactin acts to block it. In any event, I remain receptive to any ideas that will take me to where I want to go.
- Scott
Posted by Racer on July 24, 2004, at 12:44:35
In reply to Racer - Periactin?, posted by SLS on July 23, 2004, at 19:07:19
> Hi Racer.
>
> About 20 years ago, a doctor I was seeing suggested that I try Periactin. It was something that seemed bizarre at the time, and has not been suggested by anyone since. If you are still willing to share your story, you can e-mail me at:
>
> slsfan1776 at yahoo dot com
>
> My interests most recently were in drugs that stimulate the histamine H1 receptor. Periactin acts to block it. In any event, I remain receptive to any ideas that will take me to where I want to go.
>
>
> - ScottHere's another article about the cortisol connection:
http://www.psychiatrictimes.com/p991068.htmlI haven't read it yet -- printing it out now -- but it refers to the same pathways and should be relevant.
Posted by SLS on July 25, 2004, at 9:29:07
In reply to 'Nother article » SLS, posted by Racer on July 24, 2004, at 12:44:35
> Here's another article about the cortisol connection:
> http://www.psychiatrictimes.com/p991068.html
>
> I haven't read it yet -- printing it out now -- but it refers to the same pathways and should be relevant.
While you're at it:http://www.psychiatrictimes.com/p040592.html
I'll just skim...
- Scott
Posted by Racer on July 25, 2004, at 9:56:51
In reply to Re: 'Nother article, posted by SLS on July 25, 2004, at 9:29:07
That's the one I read before: I learned a lot from it -- although I can't remember it very well anymore -- but it finally explained the dexamethasone suppression test to me! All these years, now I finally understood it....
The DST, by the way, is sometimes used as a diagnostic aid in endogenous depression. Just learned that yesterday. I only knew of it as a diagnistic test for Cushing's, but since some people with depression test into Cushing's territory on cortisol levels, makes sense that they'd use the same test, huh?
Salivary tests for cortisol are pretty quick and easy, and I think rather cheap, too. I'm 98% certain there's no point bringing it up to Dr EyeCandy, but I'm going to talk to my next doctor about the whole thing. Are you finding anything to bring up with your doctor?
(And there was another article about psychodynamic perspectives on treatment-refractory depression; and one about non-compliance, and the importance of finding out *why* the patient was not complying -- you know, trying to find out if, say, sexual dysfunction might actually be an issue for a patient! What a novel concept! And -- really breaking new ground -- that addressing the side effects might improve compliance! The article actually said that, while one option was to wait and see if the side effects went away -- it was a BAD option, because they usually didn't and the waiting interfered with the doctor/patient relationship. Whoa! Why didn't anyone think of htat before?)
OK, 'nuf sarcasm there. Hope the links helped.
Posted by SLS on July 25, 2004, at 12:30:33
In reply to Re: 'Nother article » SLS, posted by Racer on July 25, 2004, at 9:56:51
Hi.
I was originally diagnosed and treated at Columbia / New York State Psychiatric in 1982. While there, they performed the DST on me, and lo and behold, I was a non-suppressor. I told my doctor this and we talked about mifepristone (RU-486). His main concern with that drug was its availability. How do you get it?
I e-mailed him the link to the article, so I guess it will act as a review for him. I think he is really starting to get into:
stress > cortisol > HPA > hippocampus (decreased neurogenesis) > depression
- Scott
Posted by Racer on July 25, 2004, at 15:38:34
In reply to Re: 'Nother article, posted by SLS on July 25, 2004, at 12:30:33
Will you keep me updated on his response? This is close to my heart, as if you couldn't tell. ;-D
This is the end of the thread.
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