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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 6 to 30 of 75. Go back in thread:
Posted by Phillipa on November 19, 2011, at 9:53:45
In reply to Re: Generic Zyprexa. Day one, posted by Zyprexa on November 19, 2011, at 9:45:20
Xanax the same with Greenstone being superior. I wish could afford to see with valium. As haven't taken brand in years. Phillipa
Posted by Christ_empowered on November 19, 2011, at 12:19:44
In reply to Re: Generic Zyprexa. Day one, posted by Phillipa on November 19, 2011, at 9:53:45
I think (and hope) you'll be just fine with the generic. Like SLS posted, the difference between brand and generic anticonvulsants can be so pronounced that some doctors keep patients on brand to avoid the hassle with generics (I had a doc do this with me on depakote).
Good luck, and do keep up posted.
Posted by ed_uk2010 on November 19, 2011, at 13:04:44
In reply to Re: Generic Zyprexa. Day one, posted by Christ_empowered on November 19, 2011, at 12:19:44
>Like SLS posted, the difference between brand and generic anticonvulsants can be so pronounced that some doctors keep patients on brand to avoid the hassle with generics
It's not that the difference between branded and generic anticonvulsants is greater than other types of meds, it's just that epileptics may be sensitive to small changes in blood levels and the consequences could be more severe.
Posted by SLS on November 19, 2011, at 14:12:25
In reply to Re: Generic Zyprexa. Day one » Christ_empowered, posted by ed_uk2010 on November 19, 2011, at 13:04:44
> > Like SLS posted, the difference between brand and generic anticonvulsants can be so pronounced that some doctors keep patients on brand to avoid the hassle with generics
> It's not that the difference between branded and generic anticonvulsants is greater than other types of meds, it's just that epileptics may be sensitive to small changes in blood levels and the consequences could be more severe.
This is correct. Generics are sometimes inferior - period.
- Scott
Posted by ed_uk2010 on November 19, 2011, at 14:20:38
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 14:12:25
>This is correct. Generics are sometimes inferior - period.
I didn't say that. An unstable epileptic patient could remain on the same manufacturer's generic, instead of the same manufacturer's brand.
Posted by ed_uk2010 on November 19, 2011, at 14:25:29
In reply to Re: Generic Zyprexa. Day one, posted by SLS on November 19, 2011, at 9:36:48
>My failure to respond to generic lamotrigine would be an example of this. Mylan was the worst.
Hmm, but how do you know you weren't spontaneously worse when taking the Mylan product? Even if the bioavailability is not quite the same as Lamictal, it will only be marginally different. Changes in mood are often independent of medication.
Posted by SLS on November 19, 2011, at 14:34:51
In reply to Re: Generic Zyprexa. Day one » SLS, posted by ed_uk2010 on November 19, 2011, at 14:25:29
> >My failure to respond to generic lamotrigine would be an example of this. Mylan was the worst.
>
> Hmm, but how do you know you weren't spontaneously worse when taking the Mylan product?Please, Ed.
- Scott
Posted by ed_uk2010 on November 19, 2011, at 15:34:05
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 14:34:51
>>Hmm, but how do you know you weren't spontaneously worse when taking the Mylan product?
>
> Please, Ed.I guess that only happens to the rest of us.
Posted by ed_uk2010 on November 19, 2011, at 15:34:36
In reply to Re: Generic Zyprexa. Day one, posted by Phillipa on November 19, 2011, at 9:53:45
> Xanax the same with Greenstone being superior.
Evidence, please?
Posted by ed_uk2010 on November 19, 2011, at 15:36:46
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 14:34:51
I am starting to remember why I stopped posting here.
Posted by SLS on November 19, 2011, at 15:44:31
In reply to Re: Generic Zyprexa. Day one » SLS, posted by ed_uk2010 on November 19, 2011, at 15:34:05
> >>Hmm, but how do you know you weren't spontaneously worse when taking the Mylan product?
> >
> > Please, Ed.
>
> I guess that only happens to the rest of us.
I'm sure you meant to speak only for yourself.
- Scott
Posted by ed_uk2010 on November 19, 2011, at 15:46:46
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 15:44:31
> > >>Hmm, but how do you know you weren't spontaneously worse when taking the Mylan product?
> > >
> > > Please, Ed.
> >
> > I guess that only happens to the rest of us.
>
>
> I'm sure you meant to speak only for yourself.
>
>
> - ScottNo, not a all. Virtually everyone with mental health problems gets better and worse and then better and worse.
Posted by ed_uk2010 on November 19, 2011, at 15:51:52
In reply to Re: Generic Zyprexa. Day one, posted by ed_uk2010 on November 19, 2011, at 15:46:46
>Virtually everyone with mental health problems gets better and worse and then better and worse.
...and funnily enough, not everything is due to what brand of meds you are on.
Posted by Jeroen on November 19, 2011, at 15:59:32
In reply to Re: Generic Zyprexa. Day one, posted by ed_uk2010 on November 19, 2011, at 15:51:52
Ed, did i tell you lucky the cat is no longer? :(
Posted by SLS on November 19, 2011, at 16:15:50
In reply to Re: Generic Zyprexa. Day one, posted by ed_uk2010 on November 19, 2011, at 15:51:52
> >Virtually everyone with mental health problems gets better and worse and then better and worse.
>
> ...and funnily enough, not everything is due to what brand of meds you are on.
I see nothing funny about any of this.I think most of us would like generic drugs to be equally functional as the original products.
I can't be bothered to explain why I was able to take 500 mg of Mylan lamotrigine without receiving benefit or experiencing side effects. Excipients perhaps? If I took 500 mg of GSK Lamictal, I wouldn't be able to remember my own name. Teva was better, but inadequate at 200 mg. Upon my return to Lamictal 200 mg, I was able to recapture its antidepressant effect within 48 hours. My doctor is not the only one to see defects in generic lamotrigine.
http://www.ncbi.nlm.nih.gov/pubmed?term=18695164
- Scott
Posted by ed_uk2010 on November 19, 2011, at 16:20:46
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 16:15:50
>http://www.ncbi.nlm.nih.gov/pubmed?term=18695164
That is not a very impressive study, but thanks for posting, it sure makes it feel very scientific.
Posted by Jeroen on November 19, 2011, at 16:21:06
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 16:15:50
ti took GSK 25 mg lamictal and got psychotic within the hour of taking it, no jokes, psychosis onset due lamictal, still have it.... so f*cked up
Posted by ed_uk2010 on November 19, 2011, at 16:22:17
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 16:15:50
> Upon my return to Lamictal 200 mg, I was able to recapture its antidepressant effect within 48 hours.
And what is that? You do not seem to experience much benefit from anything you take.
Posted by SLS on November 19, 2011, at 16:24:15
In reply to Re: Generic Zyprexa. Day one, posted by ed_uk2010 on November 19, 2011, at 16:22:17
> > Upon my return to Lamictal 200 mg, I was able to recapture its antidepressant effect within 48 hours.
>
> And what is that? You do not seem to experience much benefit from anything you take.
>
Nice, Ed.
- Scott
Posted by SLS on November 19, 2011, at 16:25:22
In reply to Re: Generic Zyprexa. Day one, posted by ed_uk2010 on November 19, 2011, at 16:20:46
> >http://www.ncbi.nlm.nih.gov/pubmed?term=18695164
>
> That is not a very impressive study,
What did you find so obviously wrong with it?
- Scott
Posted by ed_uk2010 on November 19, 2011, at 16:27:08
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 16:25:22
> What did you find so obviously wrong with it?
>
>
> - ScottThat it's not really a study. A small sample on a large variety of different products.
Posted by ed_uk2010 on November 19, 2011, at 16:28:32
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 16:24:15
> > > Upon my return to Lamictal 200 mg, I was able to recapture its antidepressant effect within 48 hours.
> >
> > And what is that? You do not seem to experience much benefit from anything you take.
> >
>
>
> Nice, Ed.
>
>
> - ScottI don't feel nice, just realistic.
Posted by ed_uk2010 on November 19, 2011, at 16:30:53
In reply to Generic Zyprexa. Day one, posted by Zyprexa on November 19, 2011, at 6:34:29
> So I took the first 10mg teva olanzapine. And feeling very positive about it.
Well good luck, because the people on this board will notice a difference on your behalf even if you don't.
Posted by SLS on November 19, 2011, at 16:32:02
In reply to Re: Generic Zyprexa. Day one, posted by ed_uk2010 on November 19, 2011, at 16:27:08
>
> > What did you find so obviously wrong with it?
> >
> >
> > - Scott
>
> That it's not really a study. A small sample on a large variety of different products.
What might you offer to prove your point?Oh. I forgot to ask you what your point was.
- Scott
Posted by ed_uk2010 on November 19, 2011, at 16:35:31
In reply to Re: Generic Zyprexa. Day one » ed_uk2010, posted by SLS on November 19, 2011, at 16:32:02
> >
> > > What did you find so obviously wrong with it?
> > >
> > >
> > > - Scott
> >
> > That it's not really a study. A small sample on a large variety of different products.
>
>
> What might you offer to prove your point?
>
> Oh. I forgot to ask you what your point was.
>
>
> - Scott
>
>My point was that the pubmed link didn't prove anything. I guess your body just wasn't absorbing any lamotrigine whatsoever from the Mylan product. Only mere mortals can feel worse due to reasons other than medication changes.
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